T-705RMP
T-705RMP, a phosphorylated metabolite of T-705, exhibits a very weak inhibitory effect on the IMP dehydrogenase (IMPDH) activities of the host cells, with an IC50 of 601 μM.
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- No. CAS: 356783-08-9
- Fòrmula: C10H13FN3O9P
- Peso molecular:369.20
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
T-705 can be converted to T-705RMP and T-705RTP by cellular kinases; Host cell enzymes can differentiate T-705, T-705RMP, and T-705RTP from the natural nucleotides. The level of inhibition of IMPDH by T-705RMP is about 150-fold weaker than that by Ribavirin monophosphate, and it became apparent that the antiviral effect of T-705 is not a result of the inhibition of the cellular enzyme[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 356783-08-9
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Peso molecular 369.20
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Fòrmula C10H13FN3O9P
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SMILES
O=C1N([C@@H]([C@H](O)[C@@H]2O)O[C@@H]2COP(O)(O)=O)C=C(F)N=C1C(N)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
T-705RMP Related Classifications
HY-136498 Related Classifications
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