Tau protein aggregation-IN-1

Cat. No.: HY-153427 Purity: 99.75%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Tau protein aggregation-IN-1 (Compound 0c) is a Tau protein aggregation inhibitor. Tau protein aggregation-IN-1 can be used in the study of protein folding disorders such as Alzheimer's disease, dementia, Parkinson's disease, Huntington's disease and prion-based spongiform encephalopathies.

For research use only. We do not sell to patients.

Tau protein aggregation-IN-1 Chemical Structure

CAS No. : 916179-45-8

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

355.19

Formula

C₁₇H₁₁BrN₂O₂

CAS No.

916179-45-8

Appearance

Solid

Color

Light green to green

SMILES

O=C(C1=CC=C2NC=C(C2=C1)C3=CNC4=C3C=C(Br)C=C4)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 30 mg/mL (84.46 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8154 mL	14.0770 mL	28.1539 mL
5 mM	0.5631 mL	2.8154 mL	5.6308 mL
10 mM	0.2815 mL	1.4077 mL	2.8154 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.75%

Select Batch:

Data Sheet (269 KB) SDS (252 KB)

COA (250 KB) HNMR (237 KB) LCMS (143 KB)

Handling Instructions (2659 KB)

References

[1]. Michael D Carter, et al. Treatment of protein folding disorders. WO2006125324A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.8154 mL	14.0770 mL	28.1539 mL	70.3849 mL
	5 mM	0.5631 mL	2.8154 mL	5.6308 mL	14.0770 mL
	10 mM	0.2815 mL	1.4077 mL	2.8154 mL	7.0385 mL
	15 mM	0.1877 mL	0.9385 mL	1.8769 mL	4.6923 mL
	20 mM	0.1408 mL	0.7038 mL	1.4077 mL	3.5192 mL
	25 mM	0.1126 mL	0.5631 mL	1.1262 mL	2.8154 mL
	30 mM	0.0938 mL	0.4692 mL	0.9385 mL	2.3462 mL
	40 mM	0.0704 mL	0.3519 mL	0.7038 mL	1.7596 mL
	50 mM	0.0563 mL	0.2815 mL	0.5631 mL	1.4077 mL
	60 mM	0.0469 mL	0.2346 mL	0.4692 mL	1.1731 mL
	80 mM	0.0352 mL	0.1760 mL	0.3519 mL	0.8798 mL