TD-6301
TD-6301 is a bladder-selective M2/4 muscarinic receptor antagonist. TD-6301 binds to and blocks M2/4 muscarinic receptors with high selectivity, especially human M2 receptors with strong affinity (Ki = 0.36 nM). TD-6301 inhibits volume-induced bladder contractions (ID50 = 0.075 mg/kg). TD-6301 can be used in the research of overactive bladder.
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- CAS No.: 690999-15-6
- 화학식: C40H57N5O2
- 분자량:639.91
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Ki: 0.36 nM (human M2 muscarinic receptor)
Chemical Information
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CAS No. 690999-15-6
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분자량 639.91
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화학식 C40H57N5O2
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SMILES
NC(C(C1=CC=CC=C1)(C2=CC=CC=C2)[C@H]3CN(CC3)CCCCCCCN(C4CCN(CC4)CC5=CN=CC=C5OC)C(C)C)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)