Art. -Nr.: HY-N2502

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Tetradehydropodophyllotoxin

(Synonyms: Dehydropodophyllotoxin)

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Tetradehydropodophyllotoxin possesses antifungal activity.

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Reinheit: 99.63%
CAS. Nr.: 42123-27-3
Formel: C₂₂H₁₈O₈
Molecular Weight:410.37

Speicherung:

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Tetradehydropodophyllotoxin Chemical Structure

CAS. Nr.: 42123-27-3

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Use of MCE Products

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Tetradehydropodophyllotoxin possesses antifungal activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A-431	ED₅₀	>20 μg/mL Compound: 3	Cytotoxicity against human A431 cells Cytotoxicity against human A431 cells	[PMID: 8277312]
A549	IC₅₀	106.7 μM Compound: 6'b	Cytotoxicity against Homo sapiens (human) A549 cells after 72 hr by MTT assay Cytotoxicity against Homo sapiens (human) A549 cells after 72 hr by MTT assay	10.1007/s00044-011-9937-1
BC1 cell line	ED₅₀	15.2 μg/mL Compound: 3	Cytotoxicity against human BC1 cells Cytotoxicity against human BC1 cells	[PMID: 8277312]
Col2	ED₅₀	8.9 μg/mL Compound: 3	Cytotoxicity against human Col2 cells Cytotoxicity against human Col2 cells	[PMID: 8277312]
HEK293	IC₅₀	240 μM Compound: 6'b	Cytotoxicity against Homo sapiens (human) HEK293 cells after 72 hr by MTT assay Cytotoxicity against Homo sapiens (human) HEK293 cells after 72 hr by MTT assay	10.1007/s00044-011-9937-1
HeLa	IC₅₀	8.28 μM Compound: 10	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 21570846]
HT	ED₅₀	9.7 μg/mL Compound: 3	Cytotoxicity against human HT cells Cytotoxicity against human HT cells	[PMID: 8277312]
KB	ED₅₀	4 μg/mL Compound: 4	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 2849640]
KB	ED₅₀	5 μg/mL Compound: 3	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 8277312]
KB	IC₅₀	29.1 μM Compound: 6'b	Cytotoxicity against Homo sapiens (human) KB cells after 72 hr by MTT assay Cytotoxicity against Homo sapiens (human) KB cells after 72 hr by MTT assay	10.1007/s00044-011-9937-1
KB	IC₅₀	9.79 μM Compound: 10	Cytotoxicity against human KB cells after 72 hrs by MTT assay Cytotoxicity against human KB cells after 72 hrs by MTT assay	[PMID: 21570846]
KB-V1	ED₅₀	13 μg/mL Compound: 3	Cytotoxicity against human KBV1 cells Cytotoxicity against human KBV1 cells	[PMID: 8277312]
LNCaP	ED₅₀	11.7 μg/mL Compound: 3	Cytotoxicity against human LNCAP cells Cytotoxicity against human LNCAP cells	[PMID: 8277312]
Lu1	ED₅₀	10.6 μg/mL Compound: 3	Cytotoxicity against human Lu1 cells Cytotoxicity against human Lu1 cells	[PMID: 8277312]
P388	ED₅₀	>5 μg/mL Compound: 3	Cytotoxicity in mouse P388 cells Cytotoxicity in mouse P388 cells	[PMID: 8277312]
SW480	IC₅₀	>100 μM Compound: 6'b	Cytotoxicity against Homo sapiens (human) SW480 cells after 72 hr by MTT assay Cytotoxicity against Homo sapiens (human) SW480 cells after 72 hr by MTT assay	10.1007/s00044-011-9937-1
U-373MG ATCC	ED₅₀	>20 μg/mL Compound: 3	Cytotoxicity against human U373 cells Cytotoxicity against human U373 cells	[PMID: 8277312]
ZR-75-1	ED₅₀	>20 μg/mL Compound: 3	Cytotoxicity against human ZR-75-1 cells Cytotoxicity against human ZR-75-1 cells	[PMID: 8277312]

Chemical Information

CAS. Nr. 42123-27-3
Appearance Solid
Molecular Weight 410.37
Formel C₂₂H₁₈O₈
Color White to off-white
SMILES

O=C1OCC2=C(C3=C(C(C4=CC(OC)=C(C(OC)=C4)OC)=C12)C=C5OCOC5=C3)O
Synonyms

Dehydropodophyllotoxin
Structure Classification
- Phenols
- Monophenols
- Others
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 10 mg/mL (24.37 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.4368 mL

12.1841 mL

24.3683 mL

5 mM

0.4874 mL

2.4368 mL

4.8737 mL

10 mM

0.2437 mL

1.2184 mL

2.4368 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Atta-ur-Rahman, et al. Antifungal aryltetralin lignans from leaves of Podophyllum hexandrum. Phytochemistry. Volume 40, Issue 2, September 1995, Pages 427-431

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.4368 mL	12.1841 mL	24.3683 mL	60.9206 mL
	5 mM	0.4874 mL	2.4368 mL	4.8737 mL	12.1841 mL
	10 mM	0.2437 mL	1.2184 mL	2.4368 mL	6.0921 mL
	15 mM	0.1625 mL	0.8123 mL	1.6246 mL	4.0614 mL
	20 mM	0.1218 mL	0.6092 mL	1.2184 mL	3.0460 mL

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Tetradehydropodophyllotoxin

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Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Tetradehydropodophyllotoxin

Bioactive Compound Library Max

Bioactive Compound Library

Anti-Infection Compound Library

Natural Product Library

Antifungal Compound Library

Medicine Food Homology Compound Library

Phenols Library

Traditional Chinese Medicine Active Compound Library

Plant-Sourced Natural Product Library

MCE Bioactive Compound Library

Natural Product Library Plus

Natural Product and Natural Product-Like Compound Library

Miao Ethnicity Medicine Compound Library

Tibetan Medicine Compound Library

PBCRBS Traditional Chinese Medicine Compound Library

RO5 Drug-like Natural Product Library

High-Throughput Bioactive Compound Library

High-Throughput Natural Product Library

Ancient Chinese Classical Formulas Traditional Chinese Medicine Active Compound Library

Diarrhea-Related Traditional Chinese Medicine Active Compound Library

Mongolian Medicine Compound Library

Natural Product Diversity Scaffold Library

Mass Spectrometry Natural Product Library

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Tetradehydropodophyllotoxin Related Classifications

HY-N2502 Related Classifications