TGR5 agonist 8
TGR5 agonist 8 (Compound 7i) is a TGR5 agonist with an EC₅₀ of 571 nM. TGR5 agonist 8 significantly reduced blood glucose and food intake in acute diabetic mice and long-term inhibited the mice's appetite. TGR5 agonist 8 can be used for research on diabetes and obesity.
For research use only. We do not sell to patients.
- Formula: C37H33N9
- Molecular Weight:603.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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TGR5 571 nM (EC50) |
Chemical Information
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Molecular Weight 603.72
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Formula C37H33N9
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SMILES
CC1=CC=CC(N2C=C(N=N2)CN3C=C(C4=CC=CC=C43)C5=NC6=C(N5CC7=CN(N=N7)C8=CC=CC(C)=C8C)C=CC=C6)=C1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)