1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride 

Cat. No.: HY-136160
Handling Instructions

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs.

For research use only. We do not sell to patients.

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride Chemical Structure

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride Chemical Structure

CAS No. : 2341841-02-7

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Description

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs[1].

IC50 & Target[1]

Cereblon

 

Molecular Weight

410.81

Formula

C₁₇H₁₉ClN₄O₆

CAS No.

2341841-02-7

SMILES

O=C(NCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Thalidomide 4'-oxyacetamide-alkyl-C2-amineE3 Ligase Ligand-Linker ConjugateInhibitorinhibitorinhibit

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Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride
Cat. No.:
HY-136160
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