2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride 

Cat. No.: HY-136160 Purity: 99.30%
COA
SDS
Handling Instructions Technical Support

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride is a synthetic E3 ligase ligand-linker conjugate, consisting of a cereblon ligand based on Thalidomide (HY-14658) and a linker.

For research use only. We do not sell to patients.

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride Chemical Structure

CAS No. : 2341841-02-7

Size Price Stock Quantity
Free Sample (0.1 - 0.2 mg)   Apply Now  
100 mg In-stock
250 mg In-stock
1 g In-stock
5 g   Get quote  
10 g   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride Related Antibodies

Top Publications Citing Use of Products

View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

View All Isoforms
von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride is a synthetic E3 ligase ligand-linker conjugate, consisting of a cereblon ligand based on Thalidomide (HY-14658) and a linker[1].

IC50 & Target[1]

Cereblon

 

In Vitro

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride Related Antibodies
Molecular Weight

410.81

Formula

C17H19ClN4O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation

Purity: 99.30%

SDS (393 KB)

COA (251 KB) HNMR (135 KB) RP-HPLC (87 KB) MS (177 KB)

Handling Instructions (2659 KB)
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thalidomide 4'-oxyacetamide-alkyl-C2-amine2341841-02-7E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride
Cat. No.:
HY-136160
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (393 KB) Français - FR (393 KB) Deutsch - DE (393 KB) Norwegian - NO (393 KB) Español - ES (393 KB) Swedish - SV (393 KB) Italian - IT (393 KB) Korean - KR (393 KB) Portuguese - PT (393 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.