Topixantrone
Topixantrone (BBR 3576) is an antitumor agent, and shows antitumor activity on prostate carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 156090-18-5
- Formula: C21H26N6O2
- Molecular Weight:394.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| LoVo | IC50 |
0.3 μg/mL
Compound: 13x
|
In vitro cytotoxicity on human colon adenocarcinoma (LoVo ) tumor cell line.
In vitro cytotoxicity on human colon adenocarcinoma (LoVo ) tumor cell line.
|
[PMID: 9876113] |
| LoVo | IC50 |
57 μg/mL
Compound: 13x
|
In vitro cytotoxicity on human colon adenocarcinoma resistant to doxorubicin (LoVo/Dx ) tumor cell line.
In vitro cytotoxicity on human colon adenocarcinoma resistant to doxorubicin (LoVo/Dx ) tumor cell line.
|
[PMID: 9876113] |
Chemical Information
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CAS No. 156090-18-5
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Molecular Weight 394.47
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Formula C21H26N6O2
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SMILES
O=C1C2=C(C3=NN(CCNCCO)C4=CC=C(C1=C34)NCCN(C)C)C=NC=C2
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Synonyms
BBR 3576
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)