trans-1,4-Cyclohexanedicarboxylic acid
Based on 1 Customer Validation
trans-1,4-Cyclohexanedicarboxylic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥98.0%
- CAS No.: 619-82-9
- Formula: C8H12O4
- Molecular Weight:172.18
-
Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
-
Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E1103 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
-
CAS No. 619-82-9
-
Appearance Solid
-
Molecular Weight 172.18
-
Formula C8H12O4
-
SMILES
C(O)(=O)[C@H]1CC[C@H](C(O)=O)CC1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (145.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (242 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.8079 mL | 29.0394 mL | 58.0788 mL | 145.1969 mL |
| 5 mM | 1.1616 mL | 5.8079 mL | 11.6158 mL | 29.0394 mL | |
| 10 mM | 0.5808 mL | 2.9039 mL | 5.8079 mL | 14.5197 mL | |
| 15 mM | 0.3872 mL | 1.9360 mL | 3.8719 mL | 9.6798 mL | |
| 20 mM | 0.2904 mL | 1.4520 mL | 2.9039 mL | 7.2598 mL | |
| 25 mM | 0.2323 mL | 1.1616 mL | 2.3232 mL | 5.8079 mL | |
| 30 mM | 0.1936 mL | 0.9680 mL | 1.9360 mL | 4.8399 mL | |
| 40 mM | 0.1452 mL | 0.7260 mL | 1.4520 mL | 3.6299 mL | |
| 50 mM | 0.1162 mL | 0.5808 mL | 1.1616 mL | 2.9039 mL | |
| 60 mM | 0.0968 mL | 0.4840 mL | 0.9680 mL | 2.4199 mL | |
| 80 mM | 0.0726 mL | 0.3630 mL | 0.7260 mL | 1.8150 mL | |
| 100 mM | 0.0581 mL | 0.2904 mL | 0.5808 mL | 1.4520 mL |
trans-1,4-Cyclohexanedicarboxylic acid Related Classifications
HY-W016897 Related Classifications
Powered by Bioz