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Cat. No.: HY-144229

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trans-Cephalosporin

Trans substituted cephalosporin is an effective NDM-1 inhibitor，with an IC₅₀ value of 0.13 μM.

For research use only. We do not sell to patients.

CAS No.: 2757462-75-0
Formula: C₁₆H₁₄N₂O₄S₃
Molecular Weight:394.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

trans-Cephalosporin Chemical Structure

CAS No.: 2757462-75-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Trans substituted cephalosporin is an effective NDM-1 inhibitor，with an IC₅₀ value of 0.13 μM.

IC₅₀ & Target

NDM-1

0.13 μM (IC₅₀)

All Beta-lactamase Isoforms :

Chemical Information

CAS No. 2757462-75-0
Molecular Weight 394.49
Formula C₁₆H₁₄N₂O₄S₃
SMILES

O=C(C(N12)=C(CSC3=NC4=CC=CC=C4S3)CS[C@]2([H])[C@@H](OC)C1=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hu L,et al. Stereochemically altered cephalosporins as potent inhibitors of New Delhi metallo-β-lactamases. Eur J Med Chem. 2022 Feb 4;232:114174. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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trans-Cephalosporin

All Beta-lactamase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

trans-Cephalosporin Related Classifications

HY-144229 Related Classifications