TS-IN-6
TS-IN-6 (Compound 10) is a thymidylate synthase (TS) inhibitor with an IC50 value of 0.54 μM, demonstrating significant antiproliferative activity. TS-IN-6 induces G1 phase cell cycle arrest and apoptosis (marked by substantial increases in both early and late apoptotic rates) and shows potential for research on cancers such as colon, breast, and liver cancers.
For research use only. We do not sell to patients.
- Formula: C29H22F2N6OS
- Molecular Weight:540.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 0.54 μM (TS)[1].
Chemical Information
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Molecular Weight 540.59
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Formula C29H22F2N6OS
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SMILES
CC1=CC=CC=C1N2C(SCC3=CN(C4=CC=C(F)C=C4F)N=N3)=NN=C2COC5=CC=C6C=CC=CC6=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)