Tyrosinase-IN-37
Tyrosinase-IN-37 (Compound 3c) is an effective Tyrosinase inhibitor with an IC50 of 1.02 μM, exhibiting 14 times the inhibitory effect of kojic acid (Kojic acid, HY-W050154), which has an IC50 of 14.74 μM. Tyrosinase-IN-37 can effectively prevent the browning of Rosa roxburghii. Additionally, Tyrosinase-IN-37 can also inhibit browning that is not caused by Tyrosinase.
For research use only. We do not sell to patients.
- CAS No.: 1899025-43-4
- Formula: C12H12N6S
- Molecular Weight:272.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
IC50: 1.02 μM (Tyrosinase) [1]
Chemical Information
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CAS No. 1899025-43-4
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Molecular Weight 272.33
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Formula C12H12N6S
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SMILES
CC1=CC=C(C2=NN(C3=NN=C(S)N3N)C=C2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)