Tyrosinase-IN-47
Tyrosinase-IN-47 (compound 6a) is a potent competitive tyrosinase inhibitor with an IC50 of 1.43 µM and a Ki of 0.1142 μM. Tyrosinase-IN-47 also shows inhibition activity in α-Glucosidase (IC50 = 36.26 μM) and acetylcholinesterase (IC50 = 8.26 μM). Tyrosinase-IN-47 exhibits in vitro antioxidant activity, with good scavenging ability for DPPH (IC50 = 4.75 μM) and ABTS (IC50 = 0.04 μM). Tyrosinase-IN-47 displays anti-browning effect on freshly cut potatoes. Tyrosinase-IN-47 can be used for pharmaceutical research.
For research use only. We do not sell to patients.
- Formula: C19H15NO3S
- Molecular Weight:337.39
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
α‑glucosidase 36.26 μM (IC50) |
AChE 8.26 μM (IC50) |
tyrosinase 1.43 μM (IC50) |
Chemical Information
-
Molecular Weight 337.39
-
Formula C19H15NO3S
-
SMILES
O=C1C=C(CSC2=CC=C(/N=C/C3=CC=CC=C3)C=C2)OC=C1O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)