1. Apoptosis
  2. Ferroptosis
  3. UAMC-3203 hydrochloride

UAMC-3203 hydrochloride 

Cat. No.: HY-112909A Purity: 98.82%
Handling Instructions

UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.

For research use only. We do not sell to patients.

UAMC-3203 hydrochloride Chemical Structure

UAMC-3203 hydrochloride Chemical Structure

CAS No. : 2271358-65-5

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 101 In-stock
Estimated Time of Arrival: December 31
5 mg USD 90 In-stock
Estimated Time of Arrival: December 31
10 mg USD 140 In-stock
Estimated Time of Arrival: December 31
50 mg USD 260 In-stock
Estimated Time of Arrival: December 31
100 mg USD 360 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of UAMC-3203 hydrochloride:

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Description

UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM[1].

IC50 & Target

IC50: 12 nM (Ferroptosis)[1]

In Vivo

No toxicity is observed in mice after repeated injections of UAMC-3203 (20 µmol/kg; injected intraperitoneally; daily, over a period of 4 weeks)[1].

Animal Model: Wild type mice derived from a Gpx4 fl/fl breeding[1]
Dosage: 20 µmol/kg
Administration: Injected intraperitoneally; daily, over a period of 4 weeks
Result: No toxicity was observed.
Molecular Weight

508.12

Formula

C₂₅H₃₈ClN₅O₂S

CAS No.

2271358-65-5

SMILES

O=S(C(C=C1NCC2=CC=CC=C2)=CC=C1NC3CCCCC3)(NCCN4CCNCC4)=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (98.40 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9680 mL 9.8402 mL 19.6804 mL
5 mM 0.3936 mL 1.9680 mL 3.9361 mL
10 mM 0.1968 mL 0.9840 mL 1.9680 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (4.09 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.09 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.09 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product name:
UAMC-3203 hydrochloride
Cat. No.:
HY-112909A
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