UAMC-4821
Based on 1 Customer Validation
UAMC-4821 is an inhibitor for ferroptosis with an IC50 of 5.2 nM. UAMC-4821 scavenges free radicals, blocks the lipid peroxidation, inhibits ML162 (HY-100002)-induced ferroptosis, and exhibits protective effect in HT-1080 cell. UAMC-4821 exhibits good pharmacokinetics characteristics in mouse with an oral bioavailability of 63%. UAMC-4821 can cross blood-brain barrier.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.01%
- 화학식: C15H19N3O
- 분자량:257.33
-
보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
용액&용해도
- 순도&문서
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
Appearance Solid
-
분자량 257.33
-
화학식 C15H19N3O
-
Color White to off-white
-
SMILES
NC1=CC(C2=CN=CO2)=CC=C1NC3CCCCC3
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 50 mg/mL (194.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
-
Data Sheet (272 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8861 mL | 19.4303 mL | 38.8606 mL | 97.1515 mL |
| 5 mM | 0.7772 mL | 3.8861 mL | 7.7721 mL | 19.4303 mL | |
| 10 mM | 0.3886 mL | 1.9430 mL | 3.8861 mL | 9.7152 mL | |
| 15 mM | 0.2591 mL | 1.2954 mL | 2.5907 mL | 6.4768 mL | |
| 20 mM | 0.1943 mL | 0.9715 mL | 1.9430 mL | 4.8576 mL | |
| 25 mM | 0.1554 mL | 0.7772 mL | 1.5544 mL | 3.8861 mL | |
| 30 mM | 0.1295 mL | 0.6477 mL | 1.2954 mL | 3.2384 mL | |
| 40 mM | 0.0972 mL | 0.4858 mL | 0.9715 mL | 2.4288 mL | |
| 50 mM | 0.0777 mL | 0.3886 mL | 0.7772 mL | 1.9430 mL | |
| 60 mM | 0.0648 mL | 0.3238 mL | 0.6477 mL | 1.6192 mL | |
| 80 mM | 0.0486 mL | 0.2429 mL | 0.4858 mL | 1.2144 mL | |
| 100 mM | 0.0389 mL | 0.1943 mL | 0.3886 mL | 0.9715 mL |
UAMC-4821 Related Classifications
HY-173029 Related Classifications
Powered by Bioz