2. Anti-infection
  3. HCV
  4. Uprifosbuvir

Uprifosbuvir  (Synonyms: IDX21437; MK-3682)

Cat. No.: HY-103487 Purity: 99.20%
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Uprifosbuvir is an antiviral agent. Uprifosbuvir is a NS5b inhibitor developed for the research of chronic hepatitis C virus.

For research use only. We do not sell to patients.

Uprifosbuvir Chemical Structure

Uprifosbuvir Chemical Structure

CAS No. : 1496551-77-9

Size Price Stock Quantity
1 mg USD 280 In-stock
5 mg USD 680 In-stock
10 mg USD 1100 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Uprifosbuvir Related Antibodies

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Description

Uprifosbuvir is an antiviral agent. Uprifosbuvir is a NS5b inhibitor developed for the research of chronic hepatitis C virus[1].

Clinical Trial
Molecular Weight

545.91

Formula

C22H29ClN3O9P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]([C@@](N(C=CC1=O)C(N1)=O)([H])O[C@@H]2CO[P@@](OC3=CC=CC=C3)(N[C@H](C)C(OC(C)C)=O)=O)([C@@H]2O)Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (457.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8318 mL 9.1590 mL 18.3180 mL
5 mM 0.3664 mL 1.8318 mL 3.6636 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8318 mL 9.1590 mL 18.3180 mL 45.7951 mL
5 mM 0.3664 mL 1.8318 mL 3.6636 mL 9.1590 mL
10 mM 0.1832 mL 0.9159 mL 1.8318 mL 4.5795 mL
15 mM 0.1221 mL 0.6106 mL 1.2212 mL 3.0530 mL
20 mM 0.0916 mL 0.4580 mL 0.9159 mL 2.2898 mL
25 mM 0.0733 mL 0.3664 mL 0.7327 mL 1.8318 mL
30 mM 0.0611 mL 0.3053 mL 0.6106 mL 1.5265 mL
40 mM 0.0458 mL 0.2290 mL 0.4580 mL 1.1449 mL
50 mM 0.0366 mL 0.1832 mL 0.3664 mL 0.9159 mL
60 mM 0.0305 mL 0.1527 mL 0.3053 mL 0.7633 mL
80 mM 0.0229 mL 0.1145 mL 0.2290 mL 0.5724 mL
100 mM 0.0183 mL 0.0916 mL 0.1832 mL 0.4580 mL
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Uprifosbuvir Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Uprifosbuvir1496551-77-9IDX21437 MK-3682IDX 21437IDX-21437MK3682MK 3682MK-3682HCVHepatitis C virusantiviralNS5bhepatitis C virusInhibitorinhibitorinhibit

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