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Cat. No.: HY-FLB0354A

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Urapidil hydrochloride solution

Urapidil hydrochloride solution is mainly composed of Urapidil hydrochloride (HY-B0354A). Urapidil hydrochloride is an orally active and blood-brain barrier permeability α1-adrenoceptor antagonist and 5-HT_1A receptor agonist with a pIC₅₀ of 6.13 and 4.38 against α1- and α2-adrenoceptor, respectively. Urapidil hydrochloride shows antihypertensive effect.

For research use only. We do not sell to patients.

CAS No.: 64887-14-5
Formula: C₂₀H₃₀ClN₅O₃
Molecular Weight:423.94

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Urapidil hydrochloride solution Chemical Structure

CAS No.: 64887-14-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All 5-HT Receptor Isoforms :

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 64887-14-5
Molecular Weight 423.94
Formula C₂₀H₃₀ClN₅O₃
SMILES

O=C1N(C(C=C(N1C)NCCCN2CCN(CC2)C3=CC=CC=C3OC)=O)C.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Gross, G., G. Hanft, and N. Kolassa, Urapidil and some analogues with hypotensive properties show high affinities for 5-hydroxytryptamine (5-HT) binding sites of the 5-HT1A subtype and for alpha 1-adrenoceptor binding sites. Naunyn Schmiedebergs Arch Pharmacol, 1987. 336(6): p. 597-601. [Content Brief]

[2]. Buch, J., Urapidil, a dual-acting antihypertensive agent: Current usage considerations. Adv Ther, 2010. 27(7): p. 426-43. [Content Brief]

[3]. Vanhaesebrouck S, et al. Neonatal transient respiratory depression after maternal urapidil infusion for hypertension. Eur J Pediatr. 2009 Feb;168(2):221-3. [Content Brief]

[4]. Castor G, et al. Urapidil permeates the intact blood-brain barrier. Intensive Care Med. 1994;20(4):278-81. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
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References

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Urapidil hydrochloride solution

All 5-HT Receptor Isoforms

All Adrenergic Receptor Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Urapidil hydrochloride solution Related Classifications

HY-FLB0354A Related Classifications

Bioz

Keywords

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