URAT1 inhibitor 11
URAT1 inhibitor 11 (Compound 7) is a URAT1 inhibitor with an IC50 value of 0.18 μM. URAT1 inhibitor 11 exhibits potent hypouricemic effects in hyperuricemic zebrafish induced by Potassium oxonate (HY-17511) and Xanthine sodium salt (HY-W017389).
For research use only. We do not sell to patients.
- CAS No.: 2416416-13-0
- Formula: C20H16F4N2O2
- Molecular Weight:392.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
URAT1 inhibitor 11 (60 min) is more stable than Benzbromarone (HY-B1135) in mouse liver microsomes (remaining percentage: 83.2% and 4.5%, respectively)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2416416-13-0
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Molecular Weight 392.35
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Formula C20H16F4N2O2
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SMILES
OC(CCCN(C1=CC(F)=CC=C1)C2=CC=NC3=CC=C(C(F)(F)F)C=C32)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)