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Art. -Nr.: HY-163404

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Urease-IN-13

Urease-IN-13 (compound d8) is an inhibitor of urease with an IC₅₀ value of 1.21 μM. Urease-IN-13 can be used in the study of infectious gastritis and gastric ulcer.

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CAS. Nr.: 3034860-91-5
Formel: C₁₉H₁₇N₃O₅
Molecular Weight:367.36

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Urease-IN-13 Chemical Structure

CAS. Nr.: 3034860-91-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Urease-IN-13 (compound d8) is an inhibitor of urease with an IC₅₀ value of 1.21 μM. Urease-IN-13 can be used in the study of infectious gastritis and gastric ulcer^[1].

In Vitro

Urease-IN-13 (250 μg/mL) exhibits low cytotoxicity in HepG2, SGC-7901, K562, and L-02 cells, with survival rates exceeding 87% for all these cell lines^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3034860-91-5
Molecular Weight 367.36
Formel C₁₉H₁₇N₃O₅
SMILES

O=C1OC(CC2=NNC(O2)=O)CN1C3=CC=CC=C3OCC4=CC=CC=C4
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Wang YN, et al. Synthesis and biological evaluation of triazolones/oxadiazolones as novel urease inhibitors. Bioorg Med Chem. 2024;102:117656. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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