PSD3 - pleckstrin and Sec7 domain containing 3 Gene
Also Known as EFA6D; EFA6R; HCA67
Species: Homo sapiens
About PSD3
This gene has 18 transcripts (splice variants), 172 orthologues and 15 paralogues. Broad expression in brain (RPKM 17.3), adrenal (RPKM 6.3) and 19 other tissues.
Summary
Predicted to enable guanyl-nucleotide exchange factor activity and phospholipid binding activity. Predicted to be involved in regulation of ARF protein signal transduction and regulation of catalytic activity. Predicted to be located in membrane. Predicted to be active in ruffle membrane. [provided by Alliance of Genome Resources, Apr 2022]
PSD3 Products (34)
| mRNA | Protein | Name |
|---|---|---|
| NM_001362819.2 | NP_001349748.1 | PH and SEC7 domain-containing protein 3 isoform 3 |
| NM_001412865.1 | NP_001399794.1 | PH and SEC7 domain-containing protein 3 isoform 4 |
| NM_001412866.1 | NP_001399795.1 | PH and SEC7 domain-containing protein 3 isoform 5 |
| NM_001412867.1 | NP_001399796.1 | PH and SEC7 domain-containing protein 3 isoform 6 |
| NM_001412868.1 | NP_001399797.1 | PH and SEC7 domain-containing protein 3 isoform 7 |
| NM_001412869.1 | NP_001399798.1 | PH and SEC7 domain-containing protein 3 isoform 8 |
| NM_001412870.1 | NP_001399799.1 | PH and SEC7 domain-containing protein 3 isoform 9 |
| NM_001412871.1 | NP_001399800.1 | PH and SEC7 domain-containing protein 3 isoform 10 |
| NM_001412872.1 | NP_001399801.1 | PH and SEC7 domain-containing protein 3 isoform 11 |
| NM_001412873.1 | NP_001399802.1 | PH and SEC7 domain-containing protein 3 isoform 12 |
| NM_001412874.1 | NP_001399803.1 | PH and SEC7 domain-containing protein 3 isoform 13 |
| NM_001412875.1 | NP_001399804.1 | PH and SEC7 domain-containing protein 3 isoform 14 |
| NM_001412876.1 | NP_001399805.1 | PH and SEC7 domain-containing protein 3 isoform 15 |
| NM_001412877.1 | NP_001399806.1 | PH and SEC7 domain-containing protein 3 isoform 16 |
| NM_001412879.1 | NP_001399808.1 | PH and SEC7 domain-containing protein 3 isoform 17 |
| NM_001412880.1 | NP_001399809.1 | PH and SEC7 domain-containing protein 3 isoform 18 |
| NM_001412881.1 | NP_001399810.1 | PH and SEC7 domain-containing protein 3 isoform 19 |
| NM_001412882.1 | NP_001399811.1 | PH and SEC7 domain-containing protein 3 isoform 13 |
| NM_001412883.1 | NP_001399812.1 | PH and SEC7 domain-containing protein 3 isoform 13 |
| NM_001412884.1 | NP_001399813.1 | PH and SEC7 domain-containing protein 3 isoform 20 |
| NM_001412885.1 | NP_001399814.1 | PH and SEC7 domain-containing protein 3 isoform 21 |
| NM_001412886.1 | NP_001399815.1 | PH and SEC7 domain-containing protein 3 isoform 21 |
| NM_001412887.1 | NP_001399816.1 | PH and SEC7 domain-containing protein 3 isoform 22 |
| NM_001412888.1 | NP_001399817.1 | PH and SEC7 domain-containing protein 3 isoform 21 |
| NM_001412889.1 | NP_001399818.1 | PH and SEC7 domain-containing protein 3 isoform 21 |
| NM_001412890.1 | NP_001399819.1 | PH and SEC7 domain-containing protein 3 isoform 23 |
| NM_001412891.1 | NP_001399820.1 | PH and SEC7 domain-containing protein 3 isoform 23 |
| NM_001412892.1 | NP_001399821.1 | PH and SEC7 domain-containing protein 3 isoform 25 |
| NM_001412893.1 | NP_001399822.1 | PH and SEC7 domain-containing protein 3 isoform 26 |
| NM_001412894.1 | NP_001399823.1 | PH and SEC7 domain-containing protein 3 isoform 27 |
| NM_001412895.1 | NP_001399824.1 | PH and SEC7 domain-containing protein 3 isoform 28 |
| NM_001412896.1 | NP_001399825.1 | PH and SEC7 domain-containing protein 3 isoform 29 |
| NM_015310.4 | NP_056125.3 | PH and SEC7 domain-containing protein 3 isoform 1 |
| NM_206909.3 | NP_996792.1 | PH and SEC7 domain-containing protein 3 isoform 2 |
PSD3 Protein Structure
Sec7: Sec7 domain (564 - 736)
PH_9: Pleckstrin homology domain (788 - 899)
- 0
- 200
- 400
- 600
- 800
- 1000
- 1049 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
PH and SEC7 domain-containing protein 3 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Idiopathic Peripheral Autonomic Neuropathy |
|
|
| Hepatocellular Carcinoma |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS22750 | Psmd3 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-178737S | 1,2-Dilinoleoyl-sn-glycero-3-phospho-L-serine-d3 ammonium | / | Unkown | |
| HY-178754S | 12-Dipalmitoyl-sn-glycero-3-PS-d3 ammonium | / | Unkown | |
| HY-RS11274 | PSD3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | PSD3 | VGNC | VGNC:84104 |
| Rattus norvegicus | PSD3 | RGD | RGD:1559968 |
| Canis familiaris | PSD3 | VGNC | VGNC:57309 |
| Mus musculus | PSD3 | MGD | MGI:1918215 |
| Bos taurus | PSD3 | VGNC | VGNC:57317 |
| Others | PSD3 | NCBI |
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