VEGFR-2-IN-68
VEGFR-2-IN-68 (13b) is a VEGFR-2 inhibitor, with an IC50 of 41.51 nM. VEGFR-2-IN-68 (13b) induces apoptosis and G2/M phase arrest. VEGFR-2-IN-68 (13b) exhibits anti-metastatic properties in cancer cells.
For research use only. We do not sell to patients.
- Formula: C27H25N5O2S
- Molecular Weight:483.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
VEGFR-2-IN-68 (13b) exhibits strong anti-proliferative effects against multiple cancer cell lines (IC50 values of 3.98 μM, 7.66 μM and 11.81 μM in MCF-7, HCT-116, and HepG2, respectively) while sparing normal cells (WI-38)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 483.58
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Formula C27H25N5O2S
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SMILES
CC(C1=NN(/C(S1)=N/N=C(C2=CC(NC(C3=CC=C(C=C3)C)=O)=CC=C2)\C)C4=CC=C(C=C4)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VEGFR-2-IN-68 Related Classifications
HY-173613 Related Classifications
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