VH 032 amide-alkylC5-azide
Based on 1 Customer Validation
VH 032 amide-alkylC5-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand.
For research use only. We do not sell to patients.
- Purity: 98.32%
- CAS No.: 2821804-11-7
- Formula: C28H39N7O4S
- Molecular Weight:569.72
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Chemical Information
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CAS No. 2821804-11-7
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Appearance Solid
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Molecular Weight 569.72
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Formula C28H39N7O4S
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Color White to off-white
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SMILES
[N-]=[N+]=NCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 62.5 mg/mL (109.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7552 mL | 8.7762 mL | 17.5525 mL | 43.8812 mL |
| 5 mM | 0.3510 mL | 1.7552 mL | 3.5105 mL | 8.7762 mL | |
| 10 mM | 0.1755 mL | 0.8776 mL | 1.7552 mL | 4.3881 mL | |
| 15 mM | 0.1170 mL | 0.5851 mL | 1.1702 mL | 2.9254 mL | |
| 20 mM | 0.0878 mL | 0.4388 mL | 0.8776 mL | 2.1941 mL | |
| 25 mM | 0.0702 mL | 0.3510 mL | 0.7021 mL | 1.7552 mL | |
| 30 mM | 0.0585 mL | 0.2925 mL | 0.5851 mL | 1.4627 mL | |
| 40 mM | 0.0439 mL | 0.2194 mL | 0.4388 mL | 1.0970 mL | |
| 50 mM | 0.0351 mL | 0.1755 mL | 0.3510 mL | 0.8776 mL | |
| 60 mM | 0.0293 mL | 0.1463 mL | 0.2925 mL | 0.7314 mL | |
| 80 mM | 0.0219 mL | 0.1097 mL | 0.2194 mL | 0.5485 mL | |
| 100 mM | 0.0176 mL | 0.0878 mL | 0.1755 mL | 0.4388 mL |