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Cat. No.: HY-175406

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VH032-cyclopropane-F-C4-CHO

VH032-cyclopropane-F-C4-CHO is an E3 ubiquitinase ligand-linker conjugate. VH032-cyclopropane-F-C4-CHO can be used to synthesize LC-MF-4 (HY-174981).

For research use only. We do not sell to patients.

Formula: C₃₁H₄₁FN₄O₆S
Molecular Weight:616.74

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

VH032-cyclopropane-F-C4-CHO Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

VH032-cyclopropane-F-C4-CHO is an E3 ubiquitinase ligand-linker conjugate. VH032-cyclopropane-F-C4-CHO can be used to synthesize LC-MF-4 (HY-174981)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

Molecular Weight 616.74
Formula C₃₁H₄₁FN₄O₆S
SMILES

O=CCCCCOC1=CC(C2=C(N=CS2)C)=CC=C1CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(C4(CC4)F)=O)=O)O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zheng L, et al. LC-MF-4, a Novel FGFR3 Degrader for Therapeutic Intervention in FGFR3-Altered Cancers. J Med Chem. 2025 Jul 10;68(13):13858-13871. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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VH032-cyclopropane-F-C4-CHO

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

VH032-cyclopropane-F-C4-CHO Related Classifications

HY-175406 Related Classifications

Bioz

Keywords

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