2. Apoptosis
  3. IAP
  4. XIAP degrader-1

XIAP degrader-1, a primary amine tethered small molecule, promotes the degradation of X-linked inhibitor of apoptosis protein (XIAP).

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XIAP degrader-1

XIAP degrader-1 構造式

CAS 番号 : 2803617-91-4

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 840 在庫あり
Solution
10 mM * 1 mL in DMSO USD 840 在庫あり
Solid
5 mg $650 在庫あり
10 mg $1050 在庫あり
25 mg $2100 在庫あり
50 mg $3350 在庫あり
100 mg $5400 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Based on 1 publication(s) in Google Scholar

XIAP degrader-1 関連抗体

Top Publications Citing Use of Products

IAP アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
cIAP cIAP-1 cIAP-2 XIAP

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  • 純度とドキュメンテーション

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製品説明

XIAP degrader-1, a primary amine tethered small molecule, promotes the degradation of X-linked inhibitor of apoptosis protein (XIAP).

分子量

587.75

分子式

C34H45N5O4
CAS 番号
Appearance

Solid

Color

Off-white to light yellow

SMILES

CN[C@H](C(N[C@@H]1C(N(C2=C(N([C@H]1C)C(CCCCCCCN)=O)C=CC=C2)CC3=C(C=CC=C4)C4=CC=C3OC)=O)=O)C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (170.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7014 mL 8.5070 mL 17.0140 mL
5 mM 0.3403 mL 1.7014 mL 3.4028 mL
10 mM 0.1701 mL 0.8507 mL 1.7014 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7014 mL 8.5070 mL 17.0140 mL 42.5351 mL
5 mM 0.3403 mL 1.7014 mL 3.4028 mL 8.5070 mL
10 mM 0.1701 mL 0.8507 mL 1.7014 mL 4.2535 mL
15 mM 0.1134 mL 0.5671 mL 1.1343 mL 2.8357 mL
20 mM 0.0851 mL 0.4254 mL 0.8507 mL 2.1268 mL
25 mM 0.0681 mL 0.3403 mL 0.6806 mL 1.7014 mL
30 mM 0.0567 mL 0.2836 mL 0.5671 mL 1.4178 mL
40 mM 0.0425 mL 0.2127 mL 0.4254 mL 1.0634 mL
50 mM 0.0340 mL 0.1701 mL 0.3403 mL 0.8507 mL
60 mM 0.0284 mL 0.1418 mL 0.2836 mL 0.7089 mL
80 mM 0.0213 mL 0.1063 mL 0.2127 mL 0.5317 mL
100 mM 0.0170 mL 0.0851 mL 0.1701 mL 0.4254 mL
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XIAP degrader-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

XIAP degrader-12803617-91-4XIAP degrader1XIAP degrader 1IAPInhibitorinhibitorinhibit

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製品名:
XIAP degrader-1
製品番号:
HY-115865
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