XIE62-1004-A
Based on 1 Customer Validation
XIE62-1004-A is an inducer of p62-LC3 interaction. XIE62-1004-A can bind to the ZZ-domain of p62, inducing p62 oligomerization and activating p62-dependent autophagy.
For research use only. We do not sell to patients.
- Purity: 99.89%
- CAS No.: 2421146-32-7
- Formula: C23H26ClNO3
- Molecular Weight:399.91
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Storage:
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Biological Activity
p62[1]
Chemical Information
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CAS No. 2421146-32-7
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Appearance Solid
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Molecular Weight 399.91
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Formula C23H26ClNO3
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Color White to off-white
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SMILES
OCCNCC1=CC=C(C(OCC2=CC=CC=C2)=C1)OCC3=CC=CC=C3.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL (312.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 5 mg/mL (12.50 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 2.5006 mL | 12.5028 mL | 25.0056 mL | 62.5141 mL |
| 5 mM | 0.5001 mL | 2.5006 mL | 5.0011 mL | 12.5028 mL | |
| 10 mM | 0.2501 mL | 1.2503 mL | 2.5006 mL | 6.2514 mL | |
| DMSO | 15 mM | 0.1667 mL | 0.8335 mL | 1.6670 mL | 4.1676 mL |
| 20 mM | 0.1250 mL | 0.6251 mL | 1.2503 mL | 3.1257 mL | |
| 25 mM | 0.1000 mL | 0.5001 mL | 1.0002 mL | 2.5006 mL | |
| 30 mM | 0.0834 mL | 0.4168 mL | 0.8335 mL | 2.0838 mL | |
| 40 mM | 0.0625 mL | 0.3126 mL | 0.6251 mL | 1.5629 mL | |
| 50 mM | 0.0500 mL | 0.2501 mL | 0.5001 mL | 1.2503 mL | |
| 60 mM | 0.0417 mL | 0.2084 mL | 0.4168 mL | 1.0419 mL | |
| 80 mM | 0.0313 mL | 0.1563 mL | 0.3126 mL | 0.7814 mL | |
| 100 mM | 0.0250 mL | 0.1250 mL | 0.2501 mL | 0.6251 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.