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Cat. No.: HY-N13016

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Yinyanghuo C

Yinyanghuo C is a prenylated flavonoid isolated from the leaves of Epimedium sagittatum. Yinyanghuo C increases the mRNA expression levels of endothelial cell markers and enhances cancer-associated angiogenesis in the 4T1 breast tumor-bearing model.

For research use only. We do not sell to patients.

CAS No.: 149182-47-8
Formula: C₂₀H₁₆O₅
Molecular Weight:336.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Yinyanghuo C Chemical Structure

CAS No.: 149182-47-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
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Bioz

Biological Activity

Description

In Vitro

Yinyanghuo C, with a structure featuring a gem-dimethylchromene moiety fused to C-3′ and C-4′ of its B ring, as determined via spectral and NOE analysis^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Yinyanghuo C increases the mRNA expression levels of endothelial cell markers (such as endothelial cell-specific molecule ESM-1, platelet endothelial cell adhesion molecule EndoCAM (CD31), and vascular von Willebrand factor) and enhances cancer-associated angiogenesis in the 4T1 breast tumor xenograft model^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 149182-47-8
Molecular Weight 336.34
Formula C₂₀H₁₆O₅
SMILES

O=C1C=C(OC=2C=C(O)C=C(O)C12)C3=CC=C4OC(C=CC4=C3)(C)C
Structure Classification
- Flavonoids
- Other Flavonoids
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Chen CC, et al. New prenylflavones from the leaves of Epimedium saggitatum. J Nat Prod. 1996;59(4):412-414. [Content Brief]

[2]. Yang X, et al. Analysis of pharmacological mechanisms of Yinyanghuo as treatment of erectile dysfunction with network pharmacology‐based strategy[J]. Andrologia, 2021, 53(2): e13943.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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