Yinyanghuo C 

Yinyanghuo C is a prenylated flavonoid isolated from the leaves of Epimedium sagittatum. Yinyanghuo C increases the mRNA expression levels of endothelial cell markers and enhances cancer-associated angiogenesis in the 4T1 breast tumor-bearing model^[1].

Yinyanghuo C, with a structure featuring a gem-dimethylchromene moiety fused to C-3′ and C-4′ of its B ring, as determined via spectral and NOE analysis^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Yinyanghuo C increases the mRNA expression levels of endothelial cell markers (such as endothelial cell-specific molecule ESM-1, platelet endothelial cell adhesion molecule EndoCAM (CD31), and vascular von Willebrand factor) and enhances cancer-associated angiogenesis in the 4T1 breast tumor xenograft model^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

336.34

C₂₀H₁₆O₅

149182-47-8

O=C1C=C(OC=2C=C(O)C=C(O)C12)C3=CC=C4OC(C=CC4=C3)(C)C

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Chen CC, et al. New prenylflavones from the leaves of Epimedium saggitatum. J Nat Prod. 1996;59(4):412-414.

  [2]. Yang X, et al. Analysis of pharmacological mechanisms of Yinyanghuo as treatment of erectile dysfunction with network pharmacology‐based strategy[J]. Andrologia, 2021, 53(2): e13943.