α-Synuclein inhibitor 10
Based on 1 Customer Validation
α-Synuclein inhibitor 10 (compound a8) inhibits the activity of α-Syn aggregation with low IC50 value (1.08 μM). α-Synuclein inhibitor 10 exhibits good binding affinity to α-Syn residues. α-Synuclein inhibitor 10 can be used in the research of Parkinson's disease (PD).
For research use only. We do not sell to patients.
- Purity: 99.85%
- CAS No.: 3050715-65-3
- Formula: C21H12ClNO6
- Molecular Weight:409.78
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All α-synuclein Isoforms
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Biological Activity
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α-synuclein Aggregation |
Chemical Information
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CAS No. 3050715-65-3
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Appearance Solid
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Molecular Weight 409.78
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Formula C21H12ClNO6
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Color Light yellow to yellow
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SMILES
O=C(C(C=C1C2=O)=CC(O)=C1C(C3=C2C=CC=C3O)=O)NC4=CC=C(Cl)C=C4O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 25 mg/mL (61.01 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4403 mL | 12.2017 mL | 24.4033 mL | 61.0083 mL |
| 5 mM | 0.4881 mL | 2.4403 mL | 4.8807 mL | 12.2017 mL | |
| 10 mM | 0.2440 mL | 1.2202 mL | 2.4403 mL | 6.1008 mL | |
| 15 mM | 0.1627 mL | 0.8134 mL | 1.6269 mL | 4.0672 mL | |
| 20 mM | 0.1220 mL | 0.6101 mL | 1.2202 mL | 3.0504 mL | |
| 25 mM | 0.0976 mL | 0.4881 mL | 0.9761 mL | 2.4403 mL | |
| 30 mM | 0.0813 mL | 0.4067 mL | 0.8134 mL | 2.0336 mL | |
| 40 mM | 0.0610 mL | 0.3050 mL | 0.6101 mL | 1.5252 mL | |
| 50 mM | 0.0488 mL | 0.2440 mL | 0.4881 mL | 1.2202 mL | |
| 60 mM | 0.0407 mL | 0.2034 mL | 0.4067 mL | 1.0168 mL |
α-Synuclein inhibitor 10 Related Classifications
HY-157308 Related Classifications
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