β-Endorphin (6-31), human
β-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and is one of three endorphins produced in humans. β-Endorphin can be used to reduce stress and maintain homeostasis in the body and is involved in neurological pain perception regulation.
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- CAS No.: 77761-27-4
- Formula: C131H218N34O40
- Molecular Weight:2909.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Adult male Swiss mice (22-25 g)[1]
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Dosage:0.03, 0.10, 0.30 or 1.00 μg/kg
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Administration:i.p., once
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Result:Significantly impaired retention at the doses of 0.03 and 0.10 μg/kg while not significantly affect retention as compared with the control group at the two higher doses of 0.30 and 1.00 μg/kg , but tended to increase retention as compared with the dose of 0.10 μg/kg.
Increased latencies to step-through at the two higher doses of 0.30 and 1.00 μg/kg but no effect at lower doses.
Chemical Information
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CAS No. 77761-27-4
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Molecular Weight 2909.38
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Formula C131H218N34O40
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Synonyms
β-EP (6-31), human
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Sequence
Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu
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Sequence Shortening
TSEKSQTPLVTLFKNAIIKNAYKKGE
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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