2,4′-Dichloroacetanilide

Cat. No.: HY-W028684 Purity: 99.68%: FAQs
Data Sheet SDS COA Handling Instructions

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2,4′-Dichloroacetanilide is a fungistatic agent. 2,4′-Dichloroacetanilide inhibits T. asteroides with a MIC value of 6.25 μg/mL.

For research use only. We do not sell to patients.

2,4′-Dichloroacetanilide Chemical Structure

CAS No. : 3289-75-6

Size	Price	Stock	Quantity
100 mg	USD 25	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Purity & Documentation
References
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Description

2,4′-Dichloroacetanilide is a fungistatic agent. 2,4′-Dichloroacetanilide inhibits T. asteroides with a MIC value of 6.25 μg/mL^[1].

Molecular Weight

204.05

Formula

C₈H₇Cl₂NO

CAS No.

3289-75-6

Appearance

Solid

Color

Light brown to brown

SMILES

O=C(CCl)NC(C=C1)=CC=C1Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (490.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.9008 mL	24.5038 mL	49.0076 mL
5 mM	0.9802 mL	4.9008 mL	9.8015 mL
10 mM	0.4901 mL	2.4504 mL	4.9008 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (12.25 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (12.25 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.68%

Select Batch:

Data Sheet (270 KB) SDS (615 KB)

COA (246 KB) HNMR (117 KB) RP-HPLC (193 KB) LCMS (243 KB)

Handling Instructions (2659 KB)

References

[1]. Yamazoe H, et al. [Studies on the experimental chemotherapy of dermatomycosis and candidiasis. V. On the antifungal activity for various arylhaloacetamide compounds in vitro and in vivo]. Yakugaku Zasshi. 1968 Dec;88(12):1602-9. Japanese. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.9008 mL	24.5038 mL	49.0076 mL	122.5190 mL
	5 mM	0.9802 mL	4.9008 mL	9.8015 mL	24.5038 mL
	10 mM	0.4901 mL	2.4504 mL	4.9008 mL	12.2519 mL
	15 mM	0.3267 mL	1.6336 mL	3.2672 mL	8.1679 mL
	20 mM	0.2450 mL	1.2252 mL	2.4504 mL	6.1259 mL
	25 mM	0.1960 mL	0.9802 mL	1.9603 mL	4.9008 mL
	30 mM	0.1634 mL	0.8168 mL	1.6336 mL	4.0840 mL
	40 mM	0.1225 mL	0.6126 mL	1.2252 mL	3.0630 mL
	50 mM	0.0980 mL	0.4901 mL	0.9802 mL	2.4504 mL
	60 mM	0.0817 mL	0.4084 mL	0.8168 mL	2.0420 mL
	80 mM	0.0613 mL	0.3063 mL	0.6126 mL	1.5315 mL
	100 mM	0.0490 mL	0.2450 mL	0.4901 mL	1.2252 mL