2-Chloroisonicotinic acid
Based on 1 Customer Validation
2-Chloroisonicotinic acid is a compound with anti-inflammatory properties that serves as an active intermediate. 2-Chloroisonicotinic acid can be used in inflammation-related research.
For research use only. We do not sell to patients.
- Purity: 99.96%
- CAS No.: 6313-54-8
- Formula: C6H4ClNO2
- Molecular Weight:157.56
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
HY-W015627
3,5-Dichloropyridine
-
HY-32756
5-Bromo-2-methoxypyridine
-
HY-W003037
5-Bromonicotinaldehyde
-
HY-W012634
Benzothiazole
-
HY-Y0178
4-Chloropyridine hydrochloride
-
HY-W012591
2,3-Dichloropyridine
-
HY-W017249
2-Chloronicotinic acid
-
HY-W007536
2,6-Dichloroisonicotinic acid
-
HY-32833
2-Chloro-3-pyridinol
-
HY-W002136
2,6-Dichloro-3-pyridinamine
-
HY-W016710
3,5-Dichloroisonicotinaldehyde
-
HY-W004586
4'-Chloro-2,2':6',2''-terpyridine
Biological Activity
2-Chloroisonicotinic acid can be obtained via purification after a catalytic reaction catalyzed by nitrilase-CLEAs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 6313-54-8
-
Appearance Solid
-
Molecular Weight 157.56
-
Formula C6H4ClNO2
-
Color Off-white to light yellow
-
SMILES
O=C(O)C1=CC=NC(Cl)=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (634.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
-
%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
-
%+
-
+%Tween-80 + +
-
%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
-
Data Sheet (288 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.3468 mL | 31.7339 mL | 63.4679 mL | 158.6697 mL |
| 5 mM | 1.2694 mL | 6.3468 mL | 12.6936 mL | 31.7339 mL | |
| 10 mM | 0.6347 mL | 3.1734 mL | 6.3468 mL | 15.8670 mL | |
| 15 mM | 0.4231 mL | 2.1156 mL | 4.2312 mL | 10.5780 mL | |
| 20 mM | 0.3173 mL | 1.5867 mL | 3.1734 mL | 7.9335 mL | |
| 25 mM | 0.2539 mL | 1.2694 mL | 2.5387 mL | 6.3468 mL | |
| 30 mM | 0.2116 mL | 1.0578 mL | 2.1156 mL | 5.2890 mL | |
| 40 mM | 0.1587 mL | 0.7933 mL | 1.5867 mL | 3.9667 mL | |
| 50 mM | 0.1269 mL | 0.6347 mL | 1.2694 mL | 3.1734 mL | |
| 60 mM | 0.1058 mL | 0.5289 mL | 1.0578 mL | 2.6445 mL | |
| 80 mM | 0.0793 mL | 0.3967 mL | 0.7933 mL | 1.9834 mL | |
| 100 mM | 0.0635 mL | 0.3173 mL | 0.6347 mL | 1.5867 mL |
2-Chloroisonicotinic acid Related Classifications
HY-65003 Related Classifications
Powered by Bioz