2-Iodoethanol
Based on 1 Customer Validation
2-Iodoethanol is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : ≥98.0%
- CAS No.: 624-76-0
- Formula: C2H5IO
- Molecular Weight:171.97
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E242 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 624-76-0
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Appearance Liquid
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Molecular Weight 171.97
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Formula C2H5IO
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Color Colorless to light yellow
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SMILES
ICCO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (581.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (240 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.8150 mL | 29.0748 mL | 58.1497 mL | 145.3742 mL |
| 5 mM | 1.1630 mL | 5.8150 mL | 11.6299 mL | 29.0748 mL | |
| 10 mM | 0.5815 mL | 2.9075 mL | 5.8150 mL | 14.5374 mL | |
| 15 mM | 0.3877 mL | 1.9383 mL | 3.8766 mL | 9.6916 mL | |
| 20 mM | 0.2907 mL | 1.4537 mL | 2.9075 mL | 7.2687 mL | |
| 25 mM | 0.2326 mL | 1.1630 mL | 2.3260 mL | 5.8150 mL | |
| 30 mM | 0.1938 mL | 0.9692 mL | 1.9383 mL | 4.8458 mL | |
| 40 mM | 0.1454 mL | 0.7269 mL | 1.4537 mL | 3.6344 mL | |
| 50 mM | 0.1163 mL | 0.5815 mL | 1.1630 mL | 2.9075 mL | |
| 60 mM | 0.0969 mL | 0.4846 mL | 0.9692 mL | 2.4229 mL | |
| 80 mM | 0.0727 mL | 0.3634 mL | 0.7269 mL | 1.8172 mL | |
| 100 mM | 0.0581 mL | 0.2907 mL | 0.5815 mL | 1.4537 mL |
2-Iodoethanol Related Classifications
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