country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-188170

Copy Link Print Information

2-(N-Piperidinomethyl)chroman

2-(N-Piperidinomethyl) chroman is a chroman derivative α-adrenergic receptor antagonist. 2-(N-Piperidinomethyl) chroman competitively blocks presynaptic α2-adrenergic receptors and postsynaptic α1-adrenergic receptors. 2-(N-Piperidinomethyl) chroman can be used in research related to diseases mediated by postsynaptic α-adrenergic receptors.

For research use only. We do not sell to patients.

CAS No.: 99290-94-5
Formula: C₁₅H₂₁NO
Molecular Weight:231.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

2-(N-Piperidinomethyl)chroman Chemical Structure

CAS No.: 99290-94-5

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

^[1]

α1-adrenergic receptor

α2-adrenergic receptor

All Adrenergic Receptor Isoforms :

In Vitro

2-(N-Piperidinomethyl) chroman antagonizes the inhibitory effect of Clonidine (HY-12721) on twitch responses and antagonizes Phenylephrine (HY-B0769)-induced tissue contraction in isolated rat vas deferens tissue experiments in vitro^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

In Vivo

2-(N-Piperidinomethyl) chroman (1 mg/kg; i.v.) antagonizes α-adrenergic agonist-induced pressor responses in a spinal cord-transected rat model and competitively antagonizes the pressor effects elicited by the α2 agonist M7 and the α1 agonist Cirazoline (HY-113985)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 99290-94-5
Molecular Weight 231.34
Formula C₁₅H₂₁NO
SMILES

O1C=2C=CC=CC2CCC1CN3CCCCC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Mouillé P, et al. In vivo and in vitro study of (N-piperidinomethyl)-2-chromanne on pre- and postsynaptic alpha-adrenoreceptors in the rat. J Pharmacol. 1985 Apr;16(2):181-189.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote