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  3. 3,4,5-Trihydroxycinnamic acid decyl ester

3,4,5-Trihydroxycinnamic acid decyl ester 

Cat. No.: HY-131999
Handling Instructions

3,4,5-Trihydroxycinnamic acid decyl ester is an excellent inhibitor of lipid absorption and accumulation, with anti-obesity properties. 3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor, with an EC50 of approximately 0.9 μM.

For research use only. We do not sell to patients.

3,4,5-Trihydroxycinnamic acid decyl ester Chemical Structure

3,4,5-Trihydroxycinnamic acid decyl ester Chemical Structure

CAS No. : 1770778-45-4

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Description

3,4,5-Trihydroxycinnamic acid decyl ester is an excellent inhibitor of lipid absorption and accumulation, with anti-obesity properties. 3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor, with an EC50 of approximately 0.9 μM[1].

IC50 & Target

EC50: 0.9 μM (pancreatic lipase)[1]

In Vitro

3,4,5-Trihydroxycinnamic acid decyl ester (30 μM) exhibits an inhibitory potency of approximately 92% for pancreatic lipase in vitro[1].
3,4,5-Trihydroxycinnamic acid decyl ester (0.1-40 μM) inhibits pancreatic lipase activity in dose-dependent manner, with an EC50 value being approximately 0.9 μM[1].
3,4,5-Trihydroxycinnamic acid decyl ester inhibits pancreatic lipase in vitro and lipid accumulation during 3T3-L1 cell differentiation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

3,4,5-Trihydroxycinnamic acid decyl ester (30-150 mg/kg; p.o.) suppresses a rise in blood triglyceride (TG) levels in mice given corn oil orally[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6 weeks old Male ddY mice[1]
Dosage: 30 mg/kg, 150 mg/kg
Administration: Oral administration
Result: Reduced plasma TG in a dose-dependent manner.
Molecular Weight

336.42

Formula

C₁₉H₂₈O₅

CAS No.

1770778-45-4

SMILES

O=C(OCCCCCCCCCC)/C=C/C1=CC(O)=C(O)C(O)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

3,4,5-Trihydroxycinnamic acid decyl esterOtherslipaseinhibitoryactivityobesitydiabetesInhibitorinhibitorinhibit

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Product Name:
3,4,5-Trihydroxycinnamic acid decyl ester
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HY-131999
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