4-(2-Chloroethoxy)benzaldehyde
Based on 1 Customer Validation
4-(2-Chloroethoxy)benzaldehyde is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.61%
- CAS No.: 54373-15-8
- Formula: C9H9ClO2
- Molecular Weight:184.62
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E334 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 54373-15-8
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Appearance Solid
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Molecular Weight 184.62
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Formula C9H9ClO2
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Color Off-white to light yellow
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SMILES
O=CC1=CC=C(OCCCl)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (541.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (241 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.4165 mL | 27.0827 mL | 54.1653 mL | 135.4133 mL |
| 5 mM | 1.0833 mL | 5.4165 mL | 10.8331 mL | 27.0827 mL | |
| 10 mM | 0.5417 mL | 2.7083 mL | 5.4165 mL | 13.5413 mL | |
| 15 mM | 0.3611 mL | 1.8055 mL | 3.6110 mL | 9.0276 mL | |
| 20 mM | 0.2708 mL | 1.3541 mL | 2.7083 mL | 6.7707 mL | |
| 25 mM | 0.2167 mL | 1.0833 mL | 2.1666 mL | 5.4165 mL | |
| 30 mM | 0.1806 mL | 0.9028 mL | 1.8055 mL | 4.5138 mL | |
| 40 mM | 0.1354 mL | 0.6771 mL | 1.3541 mL | 3.3853 mL | |
| 50 mM | 0.1083 mL | 0.5417 mL | 1.0833 mL | 2.7083 mL | |
| 60 mM | 0.0903 mL | 0.4514 mL | 0.9028 mL | 2.2569 mL | |
| 80 mM | 0.0677 mL | 0.3385 mL | 0.6771 mL | 1.6927 mL | |
| 100 mM | 0.0542 mL | 0.2708 mL | 0.5417 mL | 1.3541 mL |