4-Chloro-6,7-dimethoxyquinazoline
Based on 1 Customer Validation
4-Chloro-6,7-dimethoxyquinazoline is a quinazoline derivative. 4-Chloro-6,7-dimethoxyquinazoline exhibits a significant interaction with the AChE protein (as demonstrated by molecular docking analysis). 4-Chloro-6,7-dimethoxyquinazoline is applicable to research related to Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 13790-39-1
- Formula: C10H9ClN2O2
- Molecular Weight:224.65
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
AChE |
In Vitro
4-Chloro-6,7-dimethoxyquinazoline shows no significant inhibitory effect on most cytochrome P450 isoenzymes[1].
4-Chloro-6,7-dimethoxyquinazoline exhibits a significant interaction with the 4EY7 protein, with a binding energy of -7.5 kcal/mol[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 13790-39-1
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Appearance Solid
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Molecular Weight 224.65
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Formula C10H9ClN2O2
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Color Off-white to light yellow
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SMILES
COC1=CC2=NC=NC(Cl)=C2C=C1OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Protocols
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Chloro-6,7-dimethoxyquinazoline Related Classifications
HY-Y0260 Related Classifications
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