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Cat. No.: HY-Y0260

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4-Chloro-6,7-dimethoxyquinazoline

Name: 4-Chloro-6,7-dimethoxyquinazoline
Brand: MedChemExpress
SKU: HY-Y0260
Price: 25.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Customer Review

Based on 1 Customer Validation

4-Chloro-6,7-dimethoxyquinazoline is a quinazoline derivative. 4-Chloro-6,7-dimethoxyquinazoline exhibits a significant interaction with the AChE protein (as demonstrated by molecular docking analysis). 4-Chloro-6,7-dimethoxyquinazoline is applicable to research related to Alzheimer's disease.

For research use only. We do not sell to patients.

CAS No.: 13790-39-1
Formula: C₁₀H₉ClN₂O₂
Molecular Weight:224.65

Storage:

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

4-Chloro-6,7-dimethoxyquinazoline Chemical Structure

CAS No.: 13790-39-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

IC₅₀ & Target

^[1]

AChE

All Cholinesterase (ChE) Isoforms :

AChE
BChE

In Vitro

4-Chloro-6,7-dimethoxyquinazoline shows no significant inhibitory effect on most cytochrome P450 isoenzymes^[1].

4-Chloro-6,7-dimethoxyquinazoline exhibits a significant interaction with the 4EY7 protein, with a binding energy of -7.5 kcal/mol^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 13790-39-1
Appearance Solid
Molecular Weight 224.65
Formula C₁₀H₉ClN₂O₂
Color Off-white to light yellow
SMILES

COC1=CC2=NC=NC(Cl)=C2C=C1OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Asokan K, et al. Spectroscopic study, Quantum Chemical Investigations, In silico and Drug Likeness of 4-Chloro-6, 7-dimethoxyquinazoline: A potent study of new anti-alzheimer agent[J]. Indian Journal of Biochemistry and Biophysics (IJBB), 2025, 62(4): 406-425.

[2]. Ji L, et al. Novel ruthenium complexes ligated with 4-anilinoquinazoline derivatives: synthesis, characterisation and preliminary evaluation of biological activity. European journal of medicinal chemistry. 2014 Apr 22;77:110-20.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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