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  2. Amino Acid Derivatives
  3. 4-Methyl-L-leucine

4-Methyl-L-leucine  (Synonyms: L-Leucine, 4-methyl- (9CI); L-2-Amino-4,4-dimethylpentanoic acid; L-γ-Methylleucine)

Cat. No.: HY-79415 Purity: ≥97.0%
COA Handling Instructions

4-Methyl-L-leucine is a Glycine (HY-Y0966) derivative.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

4-Methyl-L-leucine Chemical Structure

4-Methyl-L-leucine Chemical Structure

CAS No. : 57224-50-7

Size Price Stock Quantity
500 mg USD 250 In-stock
1 g USD 350 In-stock
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10 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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  • Biological Activity

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Description

4-Methyl-L-leucine is a Glycine (HY-Y0966) derivative[1].

In Vitro

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

145.20

Formula

C7H15NO2

CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 25 mg/mL (172.18 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.8871 mL 34.4353 mL 68.8705 mL
5 mM 1.3774 mL 6.8871 mL 13.7741 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥97.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.8871 mL 34.4353 mL 68.8705 mL 172.1763 mL
5 mM 1.3774 mL 6.8871 mL 13.7741 mL 34.4353 mL
10 mM 0.6887 mL 3.4435 mL 6.8871 mL 17.2176 mL
15 mM 0.4591 mL 2.2957 mL 4.5914 mL 11.4784 mL
20 mM 0.3444 mL 1.7218 mL 3.4435 mL 8.6088 mL
25 mM 0.2755 mL 1.3774 mL 2.7548 mL 6.8871 mL
30 mM 0.2296 mL 1.1478 mL 2.2957 mL 5.7392 mL
40 mM 0.1722 mL 0.8609 mL 1.7218 mL 4.3044 mL
50 mM 0.1377 mL 0.6887 mL 1.3774 mL 3.4435 mL
60 mM 0.1148 mL 0.5739 mL 1.1478 mL 2.8696 mL
80 mM 0.0861 mL 0.4304 mL 0.8609 mL 2.1522 mL
100 mM 0.0689 mL 0.3444 mL 0.6887 mL 1.7218 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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4-Methyl-L-leucine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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