4-O-Methylhelichrysetin
4-O-Methylhelichrysetin is a Chalcones product that can be isolated from the herbs of Cephalotaxus sinensis.
For research use only. We do not sell to patients.
- CAS No.: 56121-44-9
- Formula: C17H16O5
- Molecular Weight:300.31
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>50 μM
Compound: 11b
|
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 25629304] |
| DU-145 | GI50 |
9 μM
Compound: 6
|
Cytotoxicity against human DU145 cells after 48 hrs
Cytotoxicity against human DU145 cells after 48 hrs
|
[PMID: 18798609] |
| HeLa | IC50 |
47.7 μM
Compound: 11b
|
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 25629304] |
| HepG2 | IC50 |
18.1 μM
Compound: 11b
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
|
[PMID: 25629304] |
| HT-29 | GI50 |
21.6 μM
Compound: 6
|
Cytotoxicity against human HT29 cells after 48 hrs
Cytotoxicity against human HT29 cells after 48 hrs
|
[PMID: 18798609] |
| K562 | GI50 |
17 μM
Compound: 6
|
Cytotoxicity against human K562 cells after 48 hrs
Cytotoxicity against human K562 cells after 48 hrs
|
[PMID: 18798609] |
| M14 | GI50 |
19.6 μM
Compound: 6
|
Cytotoxicity against human M14 cells after 48 hrs
Cytotoxicity against human M14 cells after 48 hrs
|
[PMID: 18798609] |
| Macrophage | IC50 |
166.2 μM
Compound: 26
|
Toxicity against BALB/c mouse macrophage by MTT assay
Toxicity against BALB/c mouse macrophage by MTT assay
|
[PMID: 19962891] |
| MCF7 | GI50 |
17.3 μM
Compound: 6
|
Cytotoxicity against human MCF7 cells after 48 hrs
Cytotoxicity against human MCF7 cells after 48 hrs
|
[PMID: 18798609] |
| NCI-H460 | GI50 |
14 μM
Compound: 6
|
Cytotoxicity against human H460 cells after 48 hrs
Cytotoxicity against human H460 cells after 48 hrs
|
[PMID: 18798609] |
| NIH3T3 | GI50 |
6.7 μM
Compound: 6
|
Cytotoxicity against BALB mouse 3T3 cells after 48 hrs
Cytotoxicity against BALB mouse 3T3 cells after 48 hrs
|
[PMID: 18798609] |
| PC-3 | GI50 |
19.3 μM
Compound: 6
|
Cytotoxicity against human PC3 cells after 48 hrs
Cytotoxicity against human PC3 cells after 48 hrs
|
[PMID: 18798609] |
| Vero | IC50 |
>25 μM
Compound: 6
|
Antitrypanosomal activity against Trypanosoma cruzi Tulahuen C4 in african green monkey Vero cells after 120 hrs
Antitrypanosomal activity against Trypanosoma cruzi Tulahuen C4 in african green monkey Vero cells after 120 hrs
|
[PMID: 18798609] |
Chemical Information
-
CAS No. 56121-44-9
-
Molecular Weight 300.31
-
Formula C17H16O5
-
SMILES
COC(C=C1)=CC=C1/C=C/C(C2=C(C=C(C=C2O)O)OC)=O
-
Structure Classification
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)