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Cat. No.: HY-N1911

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4-O-Methylhelichrysetin

4-O-Methylhelichrysetin is a Chalcones product that can be isolated from the herbs of Cephalotaxus sinensis.

For research use only. We do not sell to patients.

Purity : 99.95%
CAS No.: 56121-44-9
Formula: C₁₇H₁₆O₅
Molecular Weight:300.31

Storage:

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

4-O-Methylhelichrysetin Chemical Structure

CAS No.: 56121-44-9

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Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
Help & FAQs
Classifications
Bioz

Biological Activity

Description

4-O-Methylhelichrysetin is a Chalcones product that can be isolated from the herbs of Cephalotaxus sinensis^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>50 μM Compound: 11b	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25629304]
DU-145	GI₅₀	9 μM Compound: 6	Cytotoxicity against human DU145 cells after 48 hrs Cytotoxicity against human DU145 cells after 48 hrs	[PMID: 18798609]
HeLa	IC₅₀	47.7 μM Compound: 11b	Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25629304]
HepG2	IC₅₀	18.1 μM Compound: 11b	Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25629304]
HT-29	GI₅₀	21.6 μM Compound: 6	Cytotoxicity against human HT29 cells after 48 hrs Cytotoxicity against human HT29 cells after 48 hrs	[PMID: 18798609]
K562	GI₅₀	17 μM Compound: 6	Cytotoxicity against human K562 cells after 48 hrs Cytotoxicity against human K562 cells after 48 hrs	[PMID: 18798609]
M14	GI₅₀	19.6 μM Compound: 6	Cytotoxicity against human M14 cells after 48 hrs Cytotoxicity against human M14 cells after 48 hrs	[PMID: 18798609]
Macrophage	IC₅₀	166.2 μM Compound: 26	Toxicity against BALB/c mouse macrophage by MTT assay Toxicity against BALB/c mouse macrophage by MTT assay	[PMID: 19962891]
MCF7	GI₅₀	17.3 μM Compound: 6	Cytotoxicity against human MCF7 cells after 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs	[PMID: 18798609]
NCI-H460	GI₅₀	14 μM Compound: 6	Cytotoxicity against human H460 cells after 48 hrs Cytotoxicity against human H460 cells after 48 hrs	[PMID: 18798609]
NIH3T3	GI₅₀	6.7 μM Compound: 6	Cytotoxicity against BALB mouse 3T3 cells after 48 hrs Cytotoxicity against BALB mouse 3T3 cells after 48 hrs	[PMID: 18798609]
PC-3	GI₅₀	19.3 μM Compound: 6	Cytotoxicity against human PC3 cells after 48 hrs Cytotoxicity against human PC3 cells after 48 hrs	[PMID: 18798609]
Vero	IC₅₀	>25 μM Compound: 6	Antitrypanosomal activity against Trypanosoma cruzi Tulahuen C4 in african green monkey Vero cells after 120 hrs Antitrypanosomal activity against Trypanosoma cruzi Tulahuen C4 in african green monkey Vero cells after 120 hrs	[PMID: 18798609]

Chemical Information

CAS No. 56121-44-9
Appearance Solid
Molecular Weight 300.31
Formula C₁₇H₁₆O₅
Color Light yellow to yellow
SMILES

COC(C=C1)=CC=C1/C=C/C(C2=C(C=C(C=C2O)O)OC)=O
Structure Classification
- Flavonoids
- Chalcones
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (166.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

3.3299 mL

16.6495 mL

33.2989 mL

5 mM

0.6660 mL

3.3299 mL

6.6598 mL

10 mM

0.3330 mL

1.6649 mL

3.3299 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage Dosage
mg/kg
Animal Weight (Per Animal) Animal Weight (Per Animal)
g
Dosing Volume (Per Animal) Dosing Volume (Per Animal)
μL
Number of Animals Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Working solution concentration: 0.22 mg/mL

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (250 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	3.3299 mL	16.6495 mL	33.2989 mL	83.2473 mL
	5 mM	0.6660 mL	3.3299 mL	6.6598 mL	16.6495 mL
	10 mM	0.3330 mL	1.6649 mL	3.3299 mL	8.3247 mL
	15 mM	0.2220 mL	1.1100 mL	2.2199 mL	5.5498 mL
	20 mM	0.1665 mL	0.8325 mL	1.6649 mL	4.1624 mL
	25 mM	0.1332 mL	0.6660 mL	1.3320 mL	3.3299 mL
	30 mM	0.1110 mL	0.5550 mL	1.1100 mL	2.7749 mL
	40 mM	0.0832 mL	0.4162 mL	0.8325 mL	2.0812 mL
	50 mM	0.0666 mL	0.3330 mL	0.6660 mL	1.6649 mL
	60 mM	0.0555 mL	0.2775 mL	0.5550 mL	1.3875 mL
	80 mM	0.0416 mL	0.2081 mL	0.4162 mL	1.0406 mL
	100 mM	0.0333 mL	0.1665 mL	0.3330 mL	0.8325 mL

Bioz

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MOQ

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100 mg

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Biological Activity
- Description
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation

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4-O-Methylhelichrysetin

Biological Activity

Description

Cellular Effect

Chemical Information

Solvent & Solubility

In Vitro:

In Vivo Dissolution Calculator

Purity & Documentation

Help & FAQs

Complete Stock Solution Preparation Table

4-O-Methylhelichrysetin Related Classifications

HY-N1911 Related Classifications

Bioz

Keywords

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