4-Vinylcyclohexene dioxide (Standard)
4-Vinylcyclohexene dioxide (Standard) is the analytical standard of 4-Vinylcyclohexene dioxide (HY-106591A). This product is intended for research and analytical applications. 4-Vinylcyclohexene dioxide (4-Vinylcyclohexene diepoxide) is an orally active metabolite of 4-vinylcyclohexene. 4-Vinylcyclohexene dioxide induces Apoptosis, increases intracellular ROS, and activates the PI3K/Akt/mTOR pathway. 4-Vinylcyclohexene dioxide selectively damages small ovarian follicles, inhibits granulosa cell function, and disrupts the male reproductive system. 4-Vinylcyclohexene dioxide can be used in the study of premature ovarian insufficiency, reproductive toxicity, and related fertility disorders.
For research use only. We do not sell to patients.
- CAS No.: 106-87-6
- Formula: C8H12O2
- Molecular Weight:140.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 106-87-6
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Molecular Weight 140.18
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Formula C8H12O2
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SMILES
C1(C2CCC3OC3C2)CO1
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Synonyms
Vinylcyclohexene diepoxide (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hu X, et al. Apoptosis induced in rats by 4-vinylcyclohexene diepoxide is associated with activation of the caspase cascades. Biol Reprod. 2001 Jul;65(1):87-93. [Content Brief]
[2]. Song W, et al. 4-vinylcyclohexene diepoxide induces apoptosis by excessive reactive oxygen species and DNA damage in human ovarian granulosa cells. Toxicol In Vitro. 2023 Sep;91:105613. [Content Brief]
[3]. Cao LB, et al. Hormone-Like Effects of 4-Vinylcyclohexene Diepoxide on Follicular Development. Front Cell Dev Biol. 2020 Jul 31;8:587. [Content Brief]
[4]. Miao Y, et al. Effects of 4-vinylcyclohexene diepoxide on the cell cycle, apoptosis, and steroid hormone secretion of goat ovarian granulosa cells. In Vitro Cell Dev Biol Anim. 2022 Mar;58(3):220-231. [Content Brief]
[5]. Kao SW, et al. Early effects of ovotoxicity induced by 4-vinylcyclohexene diepoxide in rats and mice. Reprod Toxicol. 1999 Jan-Feb;13(1):67-75. [Content Brief]
[6]. Adedara IA, et al. 4-Vinylcyclohexene diepoxide disrupts sperm characteristics, endocrine balance and redox status in testes and epididymis of rats. Redox Rep. 2017 Nov;22(6):388-398. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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