Cytidine 5'-monophosphate
Based on 2 publication(s) in Google Scholar
Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.82%
- CAS No.: 63-37-6
- 화학식: C9H14N3O8P
- 분자량:323.20
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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HY-A0181
Adenosine monophosphateAdenosine A1 Receptor Agonist -
HY-101981
Uridine 5'-monophosphateNucleotide Analogue -
HY-N5134
5'-Guanylic acidNucleotide -
HY-W013175
Uridine 5'-monophosphate disodium saltNucleotide Analogue -
HY-W010918
Adenosine 5'-diphosphate -
HY-W008915
Cytidine 5'-diphosphate trisodium salt -
HY-W010970
5'-Guanylic acid disodium saltNucleotide -
HY-101981R
Uridine 5'-monophosphate (Standard)Nucleotide Analogue -
HY-N0091
HypoxanthineEndogenous Metabolite -
HY-B2176
ATPEndogenous Metabolite -
HY-B1449
UridineNucleoside -
HY-128738
Thymidine-5'-monophosphate disodium saltNucleotide
Publications Citing Use of MedChemExpress (MCE) Cytidine 5'-monophosphate
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Customer Validation & Images
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Bio/Physico-chemical Assay
All Endogenous Metabolite Isoforms
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Biological Activity
제품 설명
IC50 & Target
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Human Endogenous Metabolite |
Microbial Metabolite |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| CCRF-CEM | IC50 |
0.1 μM
Compound: 7
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In vitro cytotoxicity of compounds were determined on Inhibition of human leukemia cell line(CCRF-CEM).
In vitro cytotoxicity of compounds were determined on Inhibition of human leukemia cell line(CCRF-CEM).
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[PMID: 8917645] |
| L1210 | ED50 |
0.05 μM
Compound: ara-CMP
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In vitro cytotoxicity with cleavage by phosphodiesterase-I concentration for 50% loss of viability was determined at 72 hours.
In vitro cytotoxicity with cleavage by phosphodiesterase-I concentration for 50% loss of viability was determined at 72 hours.
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[PMID: 3968680] |
| L1210 | IC50 |
0.41 μM
Compound: ara-CMP
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Inhibitory concentration on multidrug-resistant L1210 leukemia cells.
Inhibitory concentration on multidrug-resistant L1210 leukemia cells.
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[PMID: 1906107] |
| L1210 | IC50 |
0.43 μM
Compound: ara-CMP
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Inhibitory concentration on parentral (sensitive) L1210 leukemia cells.
Inhibitory concentration on parentral (sensitive) L1210 leukemia cells.
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[PMID: 1906107] |
In Vitro
Cytidine 5'-monophosphate is the drug intermediate for synthesis of nucleotide derivatives, that can be used in food and pharmaceutical industries[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 63-37-6
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Appearance Solid
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분자량 323.20
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화학식 C9H14N3O8P
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Color White to off-white
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SMILES
NC(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O2)=NC1=O
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Synonyms
5'-Cytidylic acid; 5'-CMP
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Structure Classification
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
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Journal Impact Factor
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Most Recent
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J Pharm Biomed Anal
A novel UHPLC-MS/MS approach for simultaneous quantification of pyrimidine metabolites in human biofluids. [Abstract]2025 Nov 15:265:117026. PMID: 40544701
Cytidine 5'-monophosphate purchased from MedChemExpress. Usage Cited in: J Pharm Biomed Anal. 2025 Nov 15:265:117026. [Abstract]
10 mmol/L ammonium formate and 0.1 % ammonium hydroxide in phase A; 20 mmol/L ammonium formate and 0.1 % ammonium hydroxide in phase B. The interfering compounds are as follows, UMP (9), CMP (10, Cytidine 5'-monophosphate) and TMP (11).
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용액&용해도
In Vitro:
H2O : 10 mg/mL (30.94 mM; ultrasonic and warming and heat to 60°C)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 11.11 mg/mL (34.37 mM); Clear solution; Need ultrasonic and warming and heat to 60°C
순도&문서
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O | 1 mM | 3.0941 mL | 15.4703 mL | 30.9406 mL | 77.3515 mL |
| 5 mM | 0.6188 mL | 3.0941 mL | 6.1881 mL | 15.4703 mL | |
| 10 mM | 0.3094 mL | 1.5470 mL | 3.0941 mL | 7.7351 mL | |
| 15 mM | 0.2063 mL | 1.0314 mL | 2.0627 mL | 5.1568 mL | |
| 20 mM | 0.1547 mL | 0.7735 mL | 1.5470 mL | 3.8676 mL | |
| 25 mM | 0.1238 mL | 0.6188 mL | 1.2376 mL | 3.0941 mL | |
| 30 mM | 0.1031 mL | 0.5157 mL | 1.0314 mL | 2.5784 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Cytidine 5'-monophosphate Related Classifications
HY-W009162 Related Classifications
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