5'-Deoxy-5'-iodouridine

Cat. No.: HY-77644 Purity: ≥95.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

5'-Deoxy-5'-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

5'-Deoxy-5'-iodouridine Chemical Structure

CAS No. : 14259-58-6

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 66	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 66	In-stock	Estimated Time of Arrival: December 31
Solid
100 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

354.10

Formula

C₉H₁₁IN₂O₅

CAS No.

14259-58-6

Appearance

Solid

Color

White to off-white

SMILES

IC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (282.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8241 mL	14.1203 mL	28.2406 mL
5 mM	0.5648 mL	2.8241 mL	5.6481 mL
10 mM	0.2824 mL	1.4120 mL	2.8241 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥95.0%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (251 KB) HNMR (204 KB)

Handling Instructions (2659 KB)

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.8241 mL	14.1203 mL	28.2406 mL	70.6015 mL
	5 mM	0.5648 mL	2.8241 mL	5.6481 mL	14.1203 mL
	10 mM	0.2824 mL	1.4120 mL	2.8241 mL	7.0602 mL
	15 mM	0.1883 mL	0.9414 mL	1.8827 mL	4.7068 mL
	20 mM	0.1412 mL	0.7060 mL	1.4120 mL	3.5301 mL
	25 mM	0.1130 mL	0.5648 mL	1.1296 mL	2.8241 mL
	30 mM	0.0941 mL	0.4707 mL	0.9414 mL	2.3534 mL
	40 mM	0.0706 mL	0.3530 mL	0.7060 mL	1.7650 mL
	50 mM	0.0565 mL	0.2824 mL	0.5648 mL	1.4120 mL
	60 mM	0.0471 mL	0.2353 mL	0.4707 mL	1.1767 mL
	80 mM	0.0353 mL	0.1765 mL	0.3530 mL	0.8825 mL
	100 mM	0.0282 mL	0.1412 mL	0.2824 mL	0.7060 mL