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Cat. No.: HY-N15436

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5-Deoxykievitone

5-Deoxykievitone, an isoflavanone found in Phaseolus species, is a GABA receptor modulator. 5-Deoxykievitone potentiates GABA-induced chloride current through α₁β₂γ_2s GABA_A receptors. 5-Deoxykievitone can be used for the research of epilepsy and anxiety.

For research use only. We do not sell to patients.

CAS No.: 74161-24-3
Formula: C₂₀H₂₀O₅
Molecular Weight:340.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

5-Deoxykievitone Chemical Structure

CAS No.: 74161-24-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
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Bioz

Biological Activity

Description

In Vitro

5-Deoxykievitone (Compound 10) (100 μM) potentiates the GABA-induced chloride current in Xenopus laevis oocytes expressing α₁β₂γ_2s GABA_A receptors, producing a mean enhancement of 361.45% at 100 μM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 74161-24-3
Molecular Weight 340.38
Formula C₂₀H₂₀O₅
SMILES

O=C1C2=CC=C(O)C(=C2OCC1C3=CC=C(O)C=C3O)CC=C(C)C
Structure Classification
- Flavonoids
- Isoflavones
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. O'Neill MJ, et al. Inducible isoflavonoids from the lima bean, Phaseolus lunatus. Phytochemistry. 1986 May 22;25(6):1315-1322.

[2]. Rueda DC, et al. HPLC-based activity profiling for GABAA receptor modulators in Adenocarpus cincinnatus. J Nat Prod. 2014;77(3):640-649. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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