1. Neuronal Signaling
  2. Monoamine Oxidase
  3. CX-157

CX-157 

Cat. No.: HY-100178
Handling Instructions

CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL.

For research use only. We do not sell to patients.

CX-157 Chemical Structure

CX-157 Chemical Structure

CAS No. : 205187-53-7

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Description

CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL.

IC50 & Target

EC50: 19.3 ng/mL (MAO-A)[1]

In Vivo

CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL. CX-157 is an investigational compound currently in development for the treatment of major depressive disorder (MDD). Mechanistic studies in animals have shown that CX-157 acts to inhibit MAO-A activity in a reversible and competitive manner, elevating brain levels of monoamine neurotransmitters[1].

Clinical Trial
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

348.27

Formula

C₁₄H₈F₄O₄S

CAS No.

205187-53-7

SMILES

FC(F)(F)COC1=CC(OC2=CC(F)=CC=C2S3(=O)=O)=C3C=C1

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
CX-157
Cat. No.:
HY-100178
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CX-157

Cat. No.: HY-100178