HIV-1 integrase inhibitor 3
HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM.
For research use only. We do not sell to patients.
- CAS No.: 1638504-56-9
- Formula: C21H22F2N4O4
- Molecular Weight:432.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 2.7 nM (INST)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HOS | CC50 |
>250 μM
Compound: 6'b
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Cytotoxicity against HOS cells assessed as reduction in cell viability after 48 hrs by ATPLite luminescence assay
Cytotoxicity against HOS cells assessed as reduction in cell viability after 48 hrs by ATPLite luminescence assay
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[PMID: 28737946] |
HIV-1 integrase inhibitor 3 (compound 4c) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. HIV-1 integrase inhibitor 3 also displays an antiviral inhibitory potency against the Q148H/G140S mutant with an EC50 of 7 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1638504-56-9
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Molecular Weight 432.42
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Formula C21H22F2N4O4
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SMILES
NC(C1=CC(CCCCCO)=CN=C1N2O)=C(C(NCC3=CC=C(F)C=C3F)=O)C2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HIV-1 integrase inhibitor 3 Related Classifications
HY-108817 Related Classifications
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