1. Membrane Transporter/Ion Channel
  2. Chloride Channel
  3. R(+)-IAA-94

R(+)-IAA-94 (Synonyms: R(+)-Methylindazone)

Cat. No.: HY-12693 Purity: 99.70% ee.: 99.94%
Handling Instructions

R(+)-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels.

For research use only. We do not sell to patients.

R(+)-IAA-94 Chemical Structure

R(+)-IAA-94 Chemical Structure

CAS No. : 54197-31-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 121 In-stock
Estimated Time of Arrival: December 31
10 mg USD 110 In-stock
Estimated Time of Arrival: December 31
50 mg USD 370 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

R(+)-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels. IC50 value: Target: IAA-94 has been employed in modulating chloride channel function to probe the dynamics and function of the channels. The high affinity of IAA-94 for the chloride channel has been exploited for isolation and reconstitution of these proteins.

Molecular Weight

357.23

Formula

C₁₇H₁₈Cl₂O₄

CAS No.

54197-31-8

SMILES

O=C(O)COC1=CC2=C(C([[email protected]@](C)(C3CCCC3)C2)=O)C(Cl)=C1Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (279.93 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7993 mL 13.9966 mL 27.9932 mL
5 mM 0.5599 mL 2.7993 mL 5.5986 mL
10 mM 0.2799 mL 1.3997 mL 2.7993 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.00 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.00 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.00 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.70% ee.: 99.94%

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

R(+)-IAA-94R(+)-MethylindazoneChloride ChannelCl− ChannelsInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
R(+)-IAA-94
Cat. No.:
HY-12693
Quantity:
MCE Japan Authorized Agent: