GSK1940029 (Synonyms: SCD inhibitor 1)

Name: GSK1940029
Brand: MedChemExpress
SKU: HY-19762
Rating: 5.0 (3 reviews)

Cat. No.: HY-19762 Purity: 99.82%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor extracted from patent WO/2009060053 A1, compound example 16.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

GSK1940029 화학구조

CAS No. : 1150701-66-8

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	견적 받기
200 mg	견적 받기

or 대량구매 문의

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 3 publication(s) in Google Scholar

3 Publications Citing Use of MCE GSK1940029

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor extracted from patent WO/2009060053 A1, compound example 16.

IC₅₀ & Target

Stearoyl-CoA Desaturase (SCD)^[1]

In Vitro

GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD), which can be used to treat and/or preventing various diseases, including those mediated by SCD enzyme, such as diseases related to elevated lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome, skin disorders such as acne, diseases or conditions related to cancer and the treatment of symptoms linked to the production of the amyloid plaque-forming Aβ42 peptide such as Alzheimer's disease^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

분자량

391.25

화학식

C₁₈H₁₆Cl₂N₄O₂

CAS No.

1150701-66-8

Appearance

Solid

Color

Light yellow to yellow

SMILES

ClC(C=CC(CN1N=NC(C(NC2=CC=C(CO)C=C2)=O)=C1C)=C3)=C3Cl

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

용액&용해도

In Vitro:

DMSO : ≥ 32 mg/mL (81.79 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5559 mL	12.7796 mL	25.5591 mL
5 mM	0.5112 mL	2.5559 mL	5.1118 mL
10 mM	0.2556 mL	1.2780 mL	2.5559 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.82%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (247 KB) LCMS (91 KB)

Handling Instructions (2659 KB)

References

[1]. Anne Marie Jeanne Bouillot, et al. 1, 2, 3-triazole derivatives for use as stearoyl-coa desaturase inhibitors . PCT Int. Appl. (2009), WO 2009060053 A1 20090514.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5559 mL	12.7796 mL	25.5591 mL	63.8978 mL
	5 mM	0.5112 mL	2.5559 mL	5.1118 mL	12.7796 mL
	10 mM	0.2556 mL	1.2780 mL	2.5559 mL	6.3898 mL
	15 mM	0.1704 mL	0.8520 mL	1.7039 mL	4.2599 mL
	20 mM	0.1278 mL	0.6390 mL	1.2780 mL	3.1949 mL
	25 mM	0.1022 mL	0.5112 mL	1.0224 mL	2.5559 mL
	30 mM	0.0852 mL	0.4260 mL	0.8520 mL	2.1299 mL
	40 mM	0.0639 mL	0.3195 mL	0.6390 mL	1.5974 mL
	50 mM	0.0511 mL	0.2556 mL	0.5112 mL	1.2780 mL
	60 mM	0.0426 mL	0.2130 mL	0.4260 mL	1.0650 mL
	80 mM	0.0319 mL	0.1597 mL	0.3195 mL	0.7987 mL

GSK1940029 Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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GSK1940029 (Synonyms: SCD inhibitor 1)

고객리뷰

GSK1940029 Related Antibodies

3 Publications Citing Use of MCE GSK1940029

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity

순도&문서

References

고객리뷰

GSK1940029 Related Antibodies

몰농도 계산기

농도 희석 계산기

Complete Stock Solution Preparation Table

GSK1940029 Related Classifications

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고객리뷰

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SAFETY DATA SHEET (SDS)

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