SuO-Val-Cit-PAB-MMAE
Based on 3 publication(s) in Google Scholar
SuO-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the peptide SuO-Val-Cit-PAB.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 98.0%
- Formule: C63H97N11O16
- Masse moléculaire:1264.51
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Stockage:
-80°C, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
Publications Citing Use of MedChemExpress (MCE) SuO-Val-Cit-PAB-MMAE
MoreVoir tous les produits spécifiques à Isoform Drug-Linker Conjugates for ADC
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Activité biologique
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Auristatin |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Masse moléculaire 1264.51
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Formule C63H97N11O16
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Color White to off-white
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SMILES
CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(ON4C(CCC4=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O)C
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Livraison
Shipping with dry ice.
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Stockage
-80°C, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
Publications (3)
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Journal Impact Factor
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Most Recent
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Pharmacol Res
Multiple protease-activated probody-drug conjugates for treating CD147-positive ovarian cancer with limited toxicity. [Abstract]2026 Mar:225:108120. PMID: 41620149 -
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Solvant et solubilité
DMSO : 50 mg/mL (39.54 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (274 KB)
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SDS (644 KB)
- English - EN (644 KB)
- Français - FR (644 KB)
- Deutsch - DE (644 KB)
- Norwegian - NO (644 KB)
- Español - ES (644 KB)
- Swedish - SV (644 KB)
- Italian - IT (644 KB)
- Korean - KR (644 KB)
- Portuguese - PT (644 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7908 mL | 3.9541 mL | 7.9082 mL | 19.7705 mL |
| 5 mM | 0.1582 mL | 0.7908 mL | 1.5816 mL | 3.9541 mL | |
| 10 mM | 0.0791 mL | 0.3954 mL | 0.7908 mL | 1.9771 mL | |
| 15 mM | 0.0527 mL | 0.2636 mL | 0.5272 mL | 1.3180 mL | |
| 20 mM | 0.0395 mL | 0.1977 mL | 0.3954 mL | 0.9885 mL | |
| 25 mM | 0.0316 mL | 0.1582 mL | 0.3163 mL | 0.7908 mL | |
| 30 mM | 0.0264 mL | 0.1318 mL | 0.2636 mL | 0.6590 mL |