SuO-Val-Cit-PAB-MMAE
Based on 3 publication(s) in Google Scholar
SuO-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the peptide SuO-Val-Cit-PAB.
For research use only. We do not sell to patients.
- Purity: 98.0%
- Formula: C63H97N11O16
- Molecular Weight:1264.51
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Storage:
-80°C, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) SuO-Val-Cit-PAB-MMAE
MoreAll Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
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Auristatin |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 1264.51
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Formula C63H97N11O16
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Color White to off-white
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SMILES
CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(ON4C(CCC4=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O)C
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Shipping
Shipping with dry ice.
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Storage
-80°C, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
Publications (3)
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Journal Impact Factor
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Most Recent
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Pharmacol Res
Multiple protease-activated probody-drug conjugates for treating CD147-positive ovarian cancer with limited toxicity. [Abstract]2026 Mar:225:108120. PMID: 41620149 -
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Solvent & Solubility
DMSO : 50 mg/mL (39.54 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (644 KB)
- English - EN (644 KB)
- Français - FR (644 KB)
- Deutsch - DE (644 KB)
- Norwegian - NO (644 KB)
- Español - ES (644 KB)
- Swedish - SV (644 KB)
- Italian - IT (644 KB)
- Korean - KR (644 KB)
- Portuguese - PT (644 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7908 mL | 3.9541 mL | 7.9082 mL | 19.7705 mL |
| 5 mM | 0.1582 mL | 0.7908 mL | 1.5816 mL | 3.9541 mL | |
| 10 mM | 0.0791 mL | 0.3954 mL | 0.7908 mL | 1.9771 mL | |
| 15 mM | 0.0527 mL | 0.2636 mL | 0.5272 mL | 1.3180 mL | |
| 20 mM | 0.0395 mL | 0.1977 mL | 0.3954 mL | 0.9885 mL | |
| 25 mM | 0.0316 mL | 0.1582 mL | 0.3163 mL | 0.7908 mL | |
| 30 mM | 0.0264 mL | 0.1318 mL | 0.2636 mL | 0.6590 mL |
SuO-Val-Cit-PAB-MMAE Related Classifications
HY-100566 Related Classifications
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