1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. 5-HT Receptor
  4. 5-HT6 Receptor Isoform
  5. 5-HT6 Receptor Modulator

5-HT6 Receptor Modulator

5-HT6 Receptor Modulators (2):

Cat. No. Product Name Effect Purity
  • HY-14539
    Modulator 99.99%
    Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia.
  • HY-N0049
    Modulator 99.46%
    Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 μM) and D4 (EC50=2 μM) receptor.