Androgen Receptor
Androgen receptor (AR) is a type of nuclear receptor that is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA-binding transcription factor that regulates gene expression. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype. Mutations in this gene are also associated with complete androgen insensitivity (CAIS).
All Product Categories
-
Androgen Receptor Inhibitors
(128)
View all products
-
Androgen Receptor Agonists
(27)
View all products
-
Androgen Receptor Antagonists
(150)
View all products
-
Androgen Receptor Activators
(3)
View all products
-
Androgen Receptor Modulators
(39)
View all products
-
Androgen Receptor Inducer
(1)
View all products
-
Androgen Receptor Degraders
(53)
View all products
-
Androgen Receptor Controls
(3)
View all products
-
Androgen Receptor Ligands
(26)
View all products
-
Androgen Receptor Proteins
(1)
View all products
-
Androgen Receptor Related Products (486)
Related Products (486)
-
Recombinant Proteins (1)
-
Antibodies (2)
-
(R)-Bicalutamide (Standard)
0 ImagesCat. No.: HY-108250RCAS No.: 113299-40-4(R)-Bicalutamide (Standard) is the analytical standard of (R)-Bicalutamide (HY-108250). This product is intended for research and analytical applications. (R)-Bicalutamide is the (R)-enantiomer of Bicalutamide (HY-14249). (R)-Bicalutamide is an androgen receptor (AR) antagonist, with antineoplastic activity. (R)-Bicalutamide is widely used for the research of prostate cancer.
-
LGD-3303 (Standard)
0 ImagesCat. No.: HY-103576RCAS No.: 917891-35-1LGD-3303 (Standard) is the analytical standard of LGD-3303 (HY-103576). This product is intended for research and analytical applications. LGD-3303 is a selective androgen receptor modulator (SARM).
-
4'-Methoxyflavonol (Standard)
0 ImagesCat. No.: HY-111803RCAS No.: 6889-78-74'-Methoxyflavonol (Standard) is the analytical standard of 4'-Methoxyflavonol (HY-111803). This product is intended for research and analytical applications. 4'-Methoxyflavonol is a flavonol. 4'-Methoxyflavonol reduces androgen receptor and increases SOD. 4'-Methoxyflavonol reduces plasma glucose, cholesterol, and triglycerides. 4'-Methoxyflavonol has anti-stress and antioxidant activities. 4'-Methoxyflavonol can be used in prostate cancer research.
-
Clascoterone-d5-1
0 ImagesCat. No.: HY-13331S2Synonyms: Cortexolone 17 alpha-propionate-d5-1; Cortexolone 17α-propionate-d5-1; CB-03-01-d5-1Clascoterone-d5-1 (Cortexolone 17 alpha-propionate-d5-1) is deuterium labeled Clascoterone. Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist.
-
Topterone
0 ImagesCat. No.: HY-U00198CAS No.: 60607-35-4Synonyms: Win 17665Topterone is a topical antiandrogen.
-
Carbazole derivative 1
0 ImagesCat. No.: HY-U00323CAS No.: 164914-28-7Synonyms: 2-Fluoro-7-[(3-pyridinyl)methyl]-9H-carbazoleCarbazole derivative 1 is a carbazole derivative which can be used to reduce androgen or oestrogen levels in mammals, including humans.
