Clascoterone-d5-1
Clascoterone-d5-1 (Cortexolone 17 alpha-propionate-d5-1) is deuterium labeled Clascoterone. Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist.
For research use only. We do not sell to patients.
- Formula: C24H29D5O5
- Molecular Weight:407.55
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled Cas 19608-29-8
-
Molecular Weight 407.55
-
Formula C24H29D5O5
-
SMILES
O=C1C([2H])([2H])C[C@@]2([C@]3(CC[C@@]4([C@](C(CO)=O)(OC(CC)=O)CC[C@]4([C@@]3(CC([2H])([2H])C2=C1[2H])[H])[H])C)[H])C
-
Synonyms
Cortexolone 17 alpha-propionate-d5-1; Cortexolone 17α-propionate-d5-1; CB-03-01-d5-1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[3]. Celasco G, et al. Biological profile of cortexolone 17alpha-propionate (CB-03-01), a new topical and peripherally selective androgen antagonist. Arzneimittelforschung. 2004;54(12):881-6. [Content Brief]
[4]. Trifu V, et al. Cortexolone 17伪-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 0路05% cream. Br J Dermatol. 2011 Jul;165(1):177-83. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)