1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N18770
    Bambusa arundinacea extract
    Bambusa arundinacea extract is rich in various bioactive compounds, including flavonoids, phenolic acids, and lignans. Bambusa arundinacea extract possesses antioxidant, anti-inflammatory, and antibacterial properties.
    Bambusa arundinacea extract
  • HY-A0112
    Cefcapene
    Inhibitor
    Cefcapene is an orally active cephem antibiotic. Cefcapene inactivates chromosome-encoded class C β-lactamases. Cefcapene can be used for antibacterial research.
    Cefcapene
  • HY-N7505
    Norchelerythrine
    Inhibitor
    Norchelerythrine is an alkaloid isolated from the roots of Zanthoxylum capense with antibacterial activity against gram-positive and gram-negative bacteria. Norchelerythrine exhibits inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis and Escherichia coli with MIC values >50 µg/mL.
    Norchelerythrine
  • HY-122450
    Pyroglutamylleucine
    Pyroglutamylleucine (pGlu-Leu) is an orally active peptide. Pyroglutamylleucine can be present in certain food protein hydrolysates and traditional Japanese fermented foods. Pyroglutamylleucine attenuates dysbiosis by increasing in the host antimicrobial peptide, Rattusin (HY-P11548).
    Pyroglutamylleucine
  • HY-N18791
    Onion oil
    Onion oil, extracted from onions, has significant antibacterial and anti-inflammatory properties, which are helpful in the study of bacterial infections, respiratory diseases, and skin abnormalities.
    Onion oil
  • HY-135470R
    Nifurpirinol (Standard)
    Nifurpirinol (P-7138) (Standard) is the analytical standard of Nifurpirinol (HY-135470). This product is intended for research and analytical applications. Nifurpirinol (P-7138) is a selective prosubstrate of bacterial nitroreductase (NTR). NTR catalyzes the reduction of nifurpirinol to generate cytotoxic metabolites that induce apoptosis in target cells. Nifurpirinol selectively ablates NTR-expressing cells such as pancreatic β cells, osteoblasts, dopaminergic neurons, and podocytes in transgenic zebrafish models. Nifurpirinol can be used in regeneration studies and disease modeling such as focal segmental glomerulosclerosis (FSGS).
    Nifurpirinol (Standard)
  • HY-161397
    NA-1-157
    Inhibitor
    NA-1-157 is a potent irreversible covalent inhibitor of the GES-5 carbapenemase, with a MIC of 0.5 μg/mL.
    NA-1-157
  • HY-P3459
    Tet-213
    Inhibitor
    Tet-213 is a antimicrobial peptide. Tet-213 has broad spectrum antibacterial activity. Tet-213 can promote infected wound repair.
    Tet-213
  • HY-B1923A
    Piperacillin hydrate
    Inhibitor
    Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin hydrate is most commonly used in combination with the β-lactamase inhibitor Tazobactam (HY-B1418).
    Piperacillin hydrate
  • HY-155970
    Urease-IN-7
    Inhibitor
    Urease-IN-7 (Compound 5k) is a competitive Urease inhibitor (IC50: 3.33 μM, Ki: 3.62 μM). Urease-IN-7 can be used for research of peptic and gastric ulcers.
    Urease-IN-7
  • HY-169160
    Anti-MRSA agent 18
    Inhibitor
    Anti-MRSA agent 18 (E17) is an inhibitor of MRSA with MIC values of 2 μg/mL for S. aureus and 4 μg/mL for MRSA, respectively. Anti-MRSA agent 18 interacts with bacterial cell membrane phosphatidylglycerol and cardiolipin, causing changes in cell membrane permeability and polarization, increased intracellular ROS, and DNA and protein leakage, thereby accelerating bacterial death.
    Anti-MRSA agent 18
  • HY-N3192
    Nervogenic acid
    Inhibitor
    Nervogenic acid is an aromatic compound that can be isolated from Piper elongatum VAHL. Nervogenic acid has antibacterial activities and antioxidative effects.
    Nervogenic acid
  • HY-142124
    Kalimantacin A
    Inhibitor
    Kalimantacin A is a potent antibiotic. Kalimantacin A shows antibacterial activity against staphylococcus including methicillin-resistant staphylococcus aureus (MRSA).
    Kalimantacin A
  • HY-P3326
    Targeting the bacterial sliding clamp peptide 46
    Inhibitor
    Targeting the bacterial sliding clamp peptide 46 is a short peptide targeting the bacterial sliding clamp(SC), inhibiting SC-dependent DNA synthesis.
    Targeting the bacterial sliding clamp peptide 46
  • HY-B1118S3
    Secnidazole-d3
    Secnidazole-d3 (RP-14539-d3; PM-185184-d3) is the deuterium labeled Secnidazole (HY-B1118). Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis.
    Secnidazole-d<sub>3</sub>
  • HY-123614
    PD 140248 hydrochloride
    Inhibitor
    PD 140248 hydrochloride is a quinolone broad-spectrum antibacterial agent with good in vitro bacteriostatic activity, especially having a significant inhibitory effect on Gram-positive bacteria.
    PD 140248 hydrochloride
  • HY-130838R
    JH-LPH-33 (Standard)
    Inhibitor
    JH-LPH-33 (Standard) is the analytical standard of JH-LPH-33. This product is intended for research and analytical applications. JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-33 displays outstanding antibiotic activity with a MIC value of 0.66 μg/mL[1].
    JH-LPH-33 (Standard)
  • HY-161336
    Alendronate prodrug-1
    Alendronate prodrug-1(compound 2) is an inhibitor of farnesyl diphosphate synthase (FPPS). Alendronate prodrug-1 has an antiproliferative effect with an IC50 value of 34.0 μM.
    Alendronate prodrug-1
  • HY-147814
    KFU-127
    Inhibitor
    KFU-127 (Compound 6b) is a broad spectrum topical antimicrobial capable of one-shot targeting of bacterial and fungal-bacterial biofilms. KFU-127 is considerably toxic for eukaryotic cells. KFU-127 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    KFU-127
  • HY-146400
    Antibacterial agent 97
    Inhibitor
    Antibacterial agent 97 (hit compound) is a potent antibacterial agent. Antibacterial agent 97 shows antibacterial activities with MIC of 16 and 16 µg/mL for Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), respectively.
    Antibacterial agent 97
Cat. No. Product Name / Synonyms Application Reactivity