DNA ligase-IN-2
DNA ligase-IN-2 (compound 2) is a potent LigA inhibitor and inhibits the DNA-independent autoadenylation activity of both full-length LigA and a truncated enzyme, LigA:AD (IC50=29 nM). DNA ligase-IN-2 effectively inhibits the growth of Staphylococcus aureus in vitro, with MIC valuse of 1, 1, and >64 μg/mL for S. aureus ATCC 29213, S. aureus ATCC 700699 and E. coli ATCC 25922, respectively.
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- CAS. Nr.: 635681-64-0
- Formel: C13H8FN3O3
- Molecular Weight:273.22
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
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DNA Ligase |
Chemical Information
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CAS. Nr. 635681-64-0
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Molecular Weight 273.22
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Formel C13H8FN3O3
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SMILES
O=C(C1=CC2=C(N=C1N)OC3=CC=C(F)C=C3C2=O)N
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DNA ligase-IN-2 Related Classifications
HY-150331 Related Classifications
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