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DNA ligase-IN-2

DNA ligase-IN-2 (compound 2) is a potent LigA inhibitor and inhibits the DNA-independent autoadenylation activity of both full-length LigA and a truncated enzyme, LigA:AD (IC50=29 nM). DNA ligase-IN-2 effectively inhibits the growth of Staphylococcus aureus in vitro, with MIC valuse of 1, 1, and >64 μg/mL for S. aureus ATCC 29213, S. aureus ATCC 700699 and E. coli ATCC 25922, respectively.

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  • CAS No.: 635681-64-0
  • Formula: C13H8FN3O3
  • Molecular Weight:273.22
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • DNA ligase-IN-2 Chemical Structure
    DNA ligase-IN-2 Chemical Structure
CAS No.: 635681-64-0
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    DNA ligase-IN-2 Chemical Structure
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  • DNA ligase-IN-2